NVX-108

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H564343

CAS#: 678-26-2

Description: NVX-108 is an exceptional oxygen transporter which increases brain tissue oxygen tension (PbtO2) when administered soon after traumatic brain injury (TBI).

Chemical Structure

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NVX-108
CAS# 678-26-2
Instruction

Theoretical Analysis

Hodoodo Cat#: H564343
Name: NVX-108
CAS#: 678-26-2
Chemical Formula: C5F12
Exact Mass: 287.98
Molecular Weight: 288.040
Elemental Analysis: C, 20.85; F, 79.15

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Perfluoropentane; Dodecafluoropentane; DDFP; NVX108; NVX 108; NVX-108

IUPAC/Chemical Name: Perfluoropentane; Dodecafluoropentane

InChi Key: NJCBUSHGCBERSK-UHFFFAOYSA-N

InChi Code: InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17

SMILES Code: FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 288.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Mullah SH, Saha BK, Abutarboush R, Walker PB, Haque A, Arnaud FG, Hazzard B, Auker CR, McCarron RM, Scultetus AH, Moon-Massat P. Perfluorocarbon NVX-108 increased cerebral oxygen tension after traumatic brain injury in rats. Brain Res. 2016 Mar 1;1634:132-139. doi: 10.1016/j.brainres.2016.01.012. Epub 2016 Jan 12. PubMed PMID: 26794250.

2: Moon-Massat PF, Abutarboush R, Pappas G, Haque A, Aligbe C, Arnaud F, Auker C, McCarron R, Scultetus A. Effects of perfluorocarbon dodecafluoropentane (NVX-108) on cerebral microvasculature in the healthy rat. Curr Drug Discov Technol. 2014;11(3):220-6. PubMed PMID: 25007887.