GNF-Pf-3539

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H564762

CAS#: NONE

Description: GNF-Pf-3539 is an inhibitor of EGF-EGFR interactions.

Chemical Structure

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GNF-Pf-3539
CAS# NONE
Instruction

Theoretical Analysis

Hodoodo Cat#: H564762
Name: GNF-Pf-3539
CAS#: NONE
Chemical Formula: C19H15ClN4O
Exact Mass: 350.09
Molecular Weight: 350.810
Elemental Analysis: C, 65.05; H, 4.31; Cl, 10.11; N, 15.97; O, 4.56

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: GNFPf-3539; GNF-Pf3539; GNF Pf-3539; GNF-Pf-3539

IUPAC/Chemical Name: 2-N-(3-Chlorophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine

InChi Key: KLRNKMZSARWWTH-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H15ClN4O/c20-13-5-3-6-14(11-13)22-19-23-17-9-2-1-8-16(17)18(24-19)21-12-15-7-4-10-25-15/h1-11H,12H2,(H2,21,22,23,24)

SMILES Code: ClC1=CC(NC2=NC(NCC3=CC=CO3)=C4C=CC=CC4=N2)=CC=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 350.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gudala S, Khan U, Kanungo N, Bandaru S, Hussain T, Parihar M, Nayarisseri A, Mundluru HP. Identification and Pharmacological Analysis of High Efficacy Small Molecule Inhibitors of EGF-EGFR Interactions in Clinical Treatment of Non-Small Cell Lung Carcinoma: a Computational Approach. Asian Pac J Cancer Prev. 2015;16(18):8191-6. PubMed PMID: 26745059.