Zymostenol
featured

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H584869

CAS#: 566-97-2

Description: Zymostenol is a late-stage precursor in the biosynthesis of cholesterol.

Chemical Structure

img
Zymostenol
CAS# 566-97-2
Instruction

Theoretical Analysis

Hodoodo Cat#: H584869
Name: Zymostenol
CAS#: 566-97-2
Chemical Formula: C27H46O
Exact Mass: 386.35
Molecular Weight: 386.664
Elemental Analysis: C, 83.87; H, 11.99; O, 4.14

Price and Availability

Size Price Availability Quantity
5mg USD 260
10mg USD 435
25mg USD 770
Bulk inquiry

Synonym: Zymostenol; Δ8-Cholesterol

IUPAC/Chemical Name: (5alpha)-cholest-8-en-3beta-ol

InChi Key: QETLKNDKQOXZRP-XTGBIJOFSA-N

InChi Code: InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-21,23-24,28H,6-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1

SMILES Code: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])C(CC[C@@]3([H])C[C@@H](O)CC[C@]43C)=C4CC[C@]12C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 386.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1. Hu, X., Wang, Y., Hao, L.-Y., et al. Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists Nat. Chem. Biol. 11(9), 141-147 (2015).

2. Hubler, Z., Allimuthu, D., Bederman, I., et al. Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination Nature 560(7718), 372-376 (2018).

3. Payré, B., de Medina, P., Boubekeur, N., et al. Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism Mol. Cancer Ther. 7(12), 3707-3718 (2008).

4. Poirot, M., and Silvente-Poirot, S. The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers Biochem. Pharmacol. 153, 75-81 (2018).