WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H565436
CAS#: 1620084-30-1
Description: Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.
Hodoodo Cat#: H565436
Name: Xylarianaphthol-1
CAS#: 1620084-30-1
Chemical Formula: C21H14O4
Exact Mass: 330.09
Molecular Weight: 330.340
Elemental Analysis: C, 76.36; H, 4.27; O, 19.37
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Synonym: Xylarianaphthol1; Xylarianaphthol 1; Xylarianaphthol-1
IUPAC/Chemical Name: 4-Methoxydinaphtho[1,2-b:1',2'-d]furan-5,8-diol
InChi Key: WJWZJXZBHYSKCI-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H14O4/c1-24-16-7-3-5-12-19-13-9-8-11-4-2-6-14(22)18(11)21(13)25-17(19)10-15(23)20(12)16/h2-10,22-23H,1H3
SMILES Code: OC1=C2C(OC)=CC=CC2=C3C4=CC=C5C=CC=C(O)C5=C4OC3=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 330.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Kotoku N, Higashimoto K, Kurioka M, Arai M, Fukuda A, Sumii Y, Sowa Y, Sakai T, Kobayashi M. Xylarianaphthol-1, a novel dinaphthofuran derivative, activates p21 promoter in a p53-independent manner. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3389-91. doi: 10.1016/j.bmcl.2014.05.083. Epub 2014 Jun 4. PubMed PMID: 24939757.