Alprafenone

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Hodoodo CAT#: H573752

CAS#: 124316-02-5

Description: Alprafenone is a Class I anti-arrythmic agent.

Chemical Structure

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Alprafenone
CAS# 124316-02-5
Instruction

Theoretical Analysis

Hodoodo Cat#: H573752
Name: Alprafenone
CAS#: 124316-02-5
Chemical Formula: C25H35NO4
Exact Mass: 413.26
Molecular Weight: 413.560
Elemental Analysis: C, 72.61; H, 8.53; N, 3.39; O, 15.47

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Alprafenone

IUPAC/Chemical Name: (+-)-3-(3-(2-Hydroxy-3-(tert-pentylamino)propoxy)-4-methoxyphenyl)-4'-methylpropiophenone

InChi Key: WUUQBRHWNUFEEB-UHFFFAOYSA-N

InChi Code: 1S/C25H35NO4/c1-6-25(3,4)26-16-21(27)17-30-24-15-19(10-14-23(24)29-5)9-13-22(28)20-11-7-18(2)8-12-20/h7-8,10-12,14-15,21,26-27H,6,9,13,16-17H2,1-5H3

SMILES Code: c1c(c(OC)ccc1CCC(=O)c1ccc(C)cc1)OC[C@@H](CNC(C)(CC)C)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 413.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

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Reconstitution Calculator

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1: Anyukhovsky EP, Rosen MR. Electrophysiologic effects of alprafenone on canine cardiac tissue. J Cardiovasc Pharmacol. 1994 Sep;24(3):411-9. PubMed PMID: 7528297.

2: Rose H, Ionescu I, Pöpping S, Fischer Y, Kammermeier H. Negative inotropic effects of the new class I antiarrhythmic agents berlafenone and alprafenone on electrically stimulated isolated cardiomyocytes. Arzneimittelforschung. 1992 Mar;42(3):289-91. PubMed PMID: 1497686.