L-2-Aminosuberic acid
featured

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H573902

CAS#: 4254-88-0

Description: L-2-Aminosuberic acid is a biochemical.

Chemical Structure

img
L-2-Aminosuberic acid
CAS# 4254-88-0
Instruction

Theoretical Analysis

Hodoodo Cat#: H573902
Name: L-2-Aminosuberic acid
CAS#: 4254-88-0
Chemical Formula: C8H15NO4
Exact Mass: 189.10
Molecular Weight: 189.211
Elemental Analysis: C, 50.78; H, 7.99; N, 7.40; O, 33.82

Price and Availability

Size Price Availability Quantity
100mg USD 260 2 Weeks
250mg USD 450 2 Weeks
1g USD 825 2 Weeks
Bulk inquiry

Synonym: (S)-2-Aminooctanedioic acid, Aminosuberic acid, L-2-Aminosuberic acid; H-Asu-OH

IUPAC/Chemical Name: (S)-2-Aminooctanedioic acid

InChi Key: YOFPFYYTUIARDI-LURJTMIESA-N

InChi Code: 1S/C8H15NO4/c9-6(8(12)13)4-2-1-3-5-7(10)11/h6H,1-5,9H2,(H,10,11)(H,12,13)/t6-/m0/s1

SMILES Code: C(=O)([C@@H](N)CCCCCC(=O)O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 189.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Čolović M, Rousseau E, Zhang Z, Lau J, Zhang C, Kuo HT, Yang H, Schaffer P, François Bénard, Lin KS. Synthesis and evaluation of an (18)F-labeled boramino acid analog of aminosuberic acid for PET imaging of the antiporter system x(C). Bioorg Med Chem Lett. 2018 Dec 1;28(22):3579-3584. doi: 10.1016/j.bmcl.2018.06.014. Epub 2018 Jun 8. PubMed PMID: 30316632.

2: Webster JM, Morton CA, Johnson BF, Yang H, Rishel MJ, Lee BD, Miao Q, Pabba C, Yapp DT, Schaffer P. Functional imaging of oxidative stress with a novel PET imaging agent, 18F-5-fluoro-L-aminosuberic acid. J Nucl Med. 2014 Apr;55(4):657-64. doi: 10.2967/jnumed.113.126664. Epub 2014 Feb 27. PubMed PMID: 24578242; PubMed Central PMCID: PMC4009729.

3: Kahnberg P, Lucke AJ, Glenn MP, Boyle GM, Tyndall JD, Parsons PG, Fairlie DP. Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid. J Med Chem. 2006 Dec 28;49(26):7611-22. PubMed PMID: 17181145.