WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H574197
CAS#: 815576-68-2
Description: (+)-Quinolactacin A1 is a fungal metabolite that inhibits acetylcholinesterase (AChE).
Hodoodo Cat#: H574197
Name: (+)-Quinolactacin A1
CAS#: 815576-68-2
Chemical Formula: C16H18N2O2
Exact Mass: 270.14
Molecular Weight: 270.330
Elemental Analysis: C, 71.09; H, 6.71; N, 10.36; O, 11.84
Synonym: (+)-Quinolactacin A1
IUPAC/Chemical Name: (3R)-2,3-dihydro-4-methyl-3-[(1S)-1-methylpropyl]-1H-pyrrolo[3,4-b]quinoline-1,9(4H)-dione
InChi Key: FLHQAMWKNPOTDV-TVQRCGJNSA-N
InChi Code: InChI=1S/C16H18N2O2/c1-4-9(2)13-14-12(16(20)17-13)15(19)10-7-5-6-8-11(10)18(14)3/h5-9,13H,4H2,1-3H3,(H,17,20)/t9-,13+/m0/s1
SMILES Code: O=C1C2=C([C@]([C@H](CC)C)([H])NC2=O)N(C)C3=C1C=CC=C3
Appearance: Solid powder
Purity: >95% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 270.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Kim, W.-G., Song, N.-K., and Yoo, I.-D. Quinolactacins A1 and A2, new acetylcholinesterase inhibitors from Penicillium citrinum. J. Antibiot. (Tokyo) 54(10), 831-835 (2001).