WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H535159
CAS#: 27527-13-5
Description: E 25 is a bioactive chemical.
Hodoodo Cat#: H535159
Name: E 25
CAS#: 27527-13-5
Chemical Formula: C26H42N2O
Exact Mass: 398.33
Molecular Weight: 398.635
Elemental Analysis: C, 78.34; H, 10.62; N, 7.03; O, 4.01
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: E 25; E-25; E25
IUPAC/Chemical Name: (1R-(1alpha,4abeta,10aalpha))-N-(2-(Diethylamino)ethyl)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxamide
InChi Key: WJYOWVDUHPEOIS-LGPLSSKUSA-N
InChi Code: InChI=1S/C26H42N2O/c1-7-28(8-2)17-16-27-24(29)26(6)15-9-14-25(5)22-12-10-20(19(3)4)18-21(22)11-13-23(25)26/h10,12,18-19,23H,7-9,11,13-17H2,1-6H3,(H,27,29)/t23-,25-,26-/m1/s1
SMILES Code: O=C([C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(C)C)C=C3)NCCN(CC)CC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 398.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Mondul AM, Weinstein SJ, Layne TM, Albanes D. Vitamin D and Cancer Risk and Mortality: State of the Science, Gaps, and Challenges. Epidemiol Rev. 2017 Jan 1;39(1):28-48. doi: 10.1093/epirev/mxx005. PMID: 28486651; PMCID: PMC5858034.
2: Rocha FR, Brüggemann AK, Francisco DS, Medeiros CS, Rosal D, Paulin E. Diaphragmatic mobility: relationship with lung function, respiratory muscle strength, dyspnea, and physical activity in daily life in patients with COPD. J Bras Pneumol. 2017 Jan-Feb;43(1):32-37. doi: 10.1590/S1806-37562016000000097. PMID: 28380186; PMCID: PMC5790674.
3: Hou W, Yang L, Li S, Yu H, Xu L, He D, Chen M, He S, Ye X, Que Y, Shih JW, Cheng T, Xia N. Construction and characterization of an infectious cDNA clone of Echovirus 25. Virus Res. 2015 Jul 2;205:41-4. doi: 10.1016/j.virusres.2015.05.011. Epub 2015 May 22. PMID: 26004198.
4: Reverdito R, Moricz AD, Campos TD, Pacheco AM Júnior, Silva RA. Mirizzi syndrome grades III and IV: surgical treatment. Rev Col Bras Cir. 2016 Jul- Aug;43(4):243-7. English, Portuguese. doi: 10.1590/0100-69912016004005. PMID: 27679943.
5: Cheatham SW, Baker R. Technical Report: Quantification of the Rockfloss® Floss Band Stretch Force at Different Elongation Lengths. J Sport Rehabil. 2019 May 16:1-13. doi: 10.1123/jsr.2019-0034. Epub ahead of print. PMID: 31094647.
6: Staiano A, Marker A, Liu M, Hayden E, Hsia D, Broyles S. Childhood Obesity Screening and Treatment Practices of Pediatric Healthcare Providers. J La State Med Soc. 2017 Jan-Feb;169(1):2-10. Epub 2017 Feb 15. PMID: 28218628; PMCID: PMC5321613.
7: Kokic V, Martinovic Kaliterna D, Radic M, Tandara L, Perkovic D. Association between vitamin D, oestradiol and interferon-gamma in female patients with inactive systemic lupus erythematosus: A cross-sectional study. J Int Med Res. 2018 Mar;46(3):1162-1171. doi: 10.1177/0300060517734686. Epub 2017 Dec 13. PMID: 29235391; PMCID: PMC5972245.
8: Plitt AR, El Ahmadieh TY, Aoun SG, Wardak Z, Barnett SL. Fractionated CyberKnife Stereotactic Radiotherapy for Perioptic Pituitary Adenomas. World Neurosurg. 2019 Jun;126:e1359-e1364. doi: 10.1016/j.wneu.2019.03.102. Epub 2019 Mar 19. PMID: 30902774.
9: Berger R, Rath W, Abele H, Garnier Y, Kuon RJ, Maul H. Reducing the Risk of Preterm Birth by Ambulatory Risk Factor Management. Dtsch Arztebl Int. 2019 Dec 13;116(50):858-864. doi: 10.3238/arztebl.2019.0858. PMID: 31931955; PMCID: PMC6970314.
10: Singh A, Singh SP, Bamezai R. Inhibitory potential of Chlorella vulgaris (E-25) on mouse skin papillomagenesis and xenobiotic detoxication system. Anticancer Res. 1999 May-Jun;19(3A):1887-91. PMID: 10470132.
11: Phattarataratip E, Kositkittiwanit N, Kajornkiatkul P, Yeunyong P, Ratanapitak R. P120 catenin expression and its correlation with E-cadherin in salivary gland neoplasms. J Oral Biol Craniofac Res. 2019 Jan-Mar;9(1):57-62. doi: 10.1016/j.jobcr.2018.09.005. Epub 2018 Sep 14. PMID: 30258767; PMCID: PMC6153422.
12: Li H, Meng Y, Pang L, Liang J, Lu H, Wang Q, Liang P, Cao J, Liu SA, Cheng J. Complete genome sequence of a new recombinant echovirus 25 strain isolated from a neonatal patient with hand, foot, and mouth disease complicated by encephalitis in Beijing, China. Virus Genes. 2015 Jun;50(3):505-8. doi: 10.1007/s11262-015-1186-9. Epub 2015 Mar 7. PMID: 25749996.
13: Cristina de LC, Del Rosario RM, Carmen Rosa A, Ana Veronica O. On the performance of trimetazidine and vitamin e as pharmacoprotection agents in cyclosporin a-induced toxicity. ISRN Pharmacol. 2013 Apr 11;2013:605640. doi: 10.1155/2013/605640. PMID: 23691353; PMCID: PMC3654278.
14: Jansen E, Viezeliene D, Beekhof P, Gremmer E, Ivanov L. Tissue-Specific Effects of Vitamin E Supplementation. Int J Mol Sci. 2016 Jul 19;17(7):1166. doi: 10.3390/ijms17071166. PMID: 27447613; PMCID: PMC4964537.
15: Sarma L, Tiku AB, Kesavan PC, Ogaki M. Evaluation of radioprotective action of a mutant (E-25) form of Chlorella vulgaris in mice. J Radiat Res. 1993 Dec;34(4):277-84. doi: 10.1269/jrr.34.277. PMID: 8176669.
16: Singh A, Singh SP, Bamezai R. Perinatal influence of Chlorella vulgaris (E-25) on hepatic drug metabolizing enzymes and lipid peroxidation. Anticancer Res. 1998 May-Jun;18(3A):1509-14. PMID: 9673362.
17: Jahanshahi M, Nikmahzar E, Sayyahi A. Vitamin E therapy prevents the accumulation of congophilic amyloid plaques and neurofibrillary tangles in the hippocampus in a rat model of Alzheimer's disease. Iran J Basic Med Sci. 2020 Jan;23(1):86-92. doi: 10.22038/IJBMS.2019.38165.9067. PMID: 32395206; PMCID: PMC7206846.
18: Montarry J, Bardou-Valette S, Mabon R, Jan PL, Fournet S, Grenier E, Petit EJ. Exploring the causes of small effective population sizes in cyst nematodes using artificial Globodera pallida populations. Proc Biol Sci. 2019 Jan 16;286(1894):20182359. doi: 10.1098/rspb.2018.2359. PMID: 30963865; PMCID: PMC6367184.
19: Chen D, Xu XY, Li R, Zang GA, Zhang Y, Wang MR, Xiong MF, Xu JR, Wang T, Fu H, Hu Q, Wu B, Yan GR, Fan TY. Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages. AAPS PharmSciTech. 2019 Nov 21;21(1):6. doi: 10.1208/s12249-019-1521-x. PMID: 31754916.
20: Vieth R. The future of "vitamin D", i.e. 25-hydroxyvitamin D, testing. Clin Biochem. 2013 Feb;46(3):189. doi: 10.1016/j.clinbiochem.2012.12.018. PMID: 23298561.
