WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H462978
CAS#: 2087490-48-8
Description: PUN 90488, also known as Thalidomide 4'-ether-alkylC5-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to Hodoodo Chemical Nomenclature (see web page: https://www.hodoodo.com/page/naming).
Hodoodo Cat#: H462978
Name: PUN 90488
CAS#: 2087490-48-8
Chemical Formula: C19H20N2O7
Exact Mass: 388.13
Molecular Weight: 388.376
Elemental Analysis: C, 58.76; H, 5.19; N, 7.21; O, 28.84
Synonym: Thalidomide 4'-ether-alkylC5-acid; PUN 90488; PUN-90488; PUN90488
IUPAC/Chemical Name: 6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexanoic acid
InChi Key: PBZGPWVWKSADLD-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H20N2O7/c22-14-9-8-12(17(25)20-14)21-18(26)11-5-4-6-13(16(11)19(21)27)28-10-3-1-2-7-15(23)24/h4-6,12H,1-3,7-10H2,(H,23,24)(H,20,22,25)
SMILES Code: OC(CCCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 388.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
