WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H535717
CAS#: 121264-06-0
Description: Pacidamycin 2 is isolated from Streptomyces coeruleorubidus; has anti-Pseudomonas aeruginosa activity.
Hodoodo Cat#: H535717
Name: Pacidamycin 2
CAS#: 121264-06-0
Chemical Formula: C39H49N9O12
Exact Mass: 835.35
Molecular Weight: 835.872
Elemental Analysis: C, 56.04; H, 5.91; N, 15.08; O, 22.97
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Pacidamycin 2; Pacidamycin-2; Pacidamycin2
IUPAC/Chemical Name: Butanamide, N-(((1-carboxy-2-phenylethyl)amino)carbonyl)alanyl-N3-(N-alanyl-3-hydroxyphenylalanyl)-N-((5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene)methyl)-N3-methyl-2,3-diamino-
InChi Key: STRJHWVSECGEPK-GBNDELNYSA-N
InChi Code: InChI=1S/C39H49N9O12/c1-20(40)32(52)43-27(17-24-11-8-12-25(49)15-24)34(54)46(4)22(3)31(41)35(55)48(19-26-18-29(50)36(60-26)47-14-13-30(51)45-39(47)59)33(53)21(2)42-38(58)44-28(37(56)57)16-23-9-6-5-7-10-23/h5-15,19-22,27-29,31,36,49-50H,16-18,40-41H2,1-4H3,(H,43,52)(H,56,57)(H2,42,44,58)(H,45,51,59)/b26-19+/t20-,21-,22?,27-,28?,29?,31?,36?/m0/s1
SMILES Code: CC(N(C([C@H](CC1=CC=CC(O)=C1)NC([C@H](C)N)=O)=O)C)C(N)C(N(C([C@H](C)NC(NC(C(O)=O)CC2=CC=CC=C2)=O)=O)/C=C3OC(N(C(N4)=O)C=CC4=O)C(O)C/3)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 835.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Fernandes PB, Swanson RN, Hardy DJ, Hanson CW, Coen L, Rasmussen RR, Chen RH. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. III. Microbiologic profile. J Antibiot (Tokyo). 1989 Apr;42(4):521-6. doi: 10.7164/antibiotics.42.521. PMID: 2498265.
2: Karwowski JP, Jackson M, Theriault RJ, Chen RH, Barlow GJ, Maus ML. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. I. Taxonomy of the producing organism and fermentation. J Antibiot (Tokyo). 1989 Apr;42(4):506-11. doi: 10.7164/antibiotics.42.506. PMID: 2498263.
3: Chen RH, Buko AM, Whittern DN, McAlpine JB. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. II. Isolation and structural elucidation. J Antibiot (Tokyo). 1989 Apr;42(4):512-20. doi: 10.7164/antibiotics.42.512. PMID: 2498264.