WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H463045
CAS#: 631-01-6
Description: Quillaic acid is a triterpene saponin that has been found in Q. saponaria bark and has diverse biological activities. It is cytotoxic to SNU-1 and KATO III gastric cancer cells. Quillaic acid induces hot plate analgesia in mice. It reduces ear edema induced by arachidonic acid or phorbol 12-myristate 13-acetate in mice when administered topically at doses of 0.7 and 1.6 mg/ear, respectively.
Hodoodo Cat#: H463045
Name: Quillaic Acid
CAS#: 631-01-6
Chemical Formula: C30H46O5
Exact Mass: 486.33
Molecular Weight: 486.693
Elemental Analysis: C, 74.04; H, 9.53; O, 16.44
Synonym: Quillaic Acid; Quillaja Sapogenin;
IUPAC/Chemical Name: (4aR,5R,6aS,6bR,8aR,9S,10S,12aR,12bR,14bS)-9-formyl-5,10-dihydroxy-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
InChi Key: MQUFAARYGOUYEV-UAWZMHPWSA-N
InChi Code: InChI=1S/C30H46O5/c1-25(2)13-14-30(24(34)35)19(15-25)18-7-8-21-26(3)11-10-22(32)27(4,17-31)20(26)9-12-28(21,5)29(18,6)16-23(30)33/h7,17,19-23,32-33H,8-16H2,1-6H3,(H,34,35)/t19-,20+,21+,22-,23+,26-,27-,28+,29+,30+/m0/s1
SMILES Code: OC([C@@]12[C@]([H])(C3=CC[C@]4([H])[C@]5(C)[C@@]([H])(CC[C@]4([C@]3(C)C[C@H]2O)C)[C@@]([C@@H](O)CC5)(C=O)C)CC(CC1)(C)C)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 486.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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