Penicillic acid
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Hodoodo CAT#: H463187

CAS#: 90-65-3

Description: Penicillic acid is a mycotoxin with antibiotic and carcinogenic activity.


Chemical Structure

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Penicillic acid
CAS# 90-65-3

Theoretical Analysis

Hodoodo Cat#: H463187
Name: Penicillic acid
CAS#: 90-65-3
Chemical Formula: C8H10O4
Exact Mass: 170.06
Molecular Weight: 170.164
Elemental Analysis: C, 56.47; H, 5.92; O, 37.61

Price and Availability

Size Price Availability Quantity
50mg USD -2 2 Weeks
100mg USD -2 2 Weeks
200mg USD -2 2 Weeks
500mg USD -2 2 Weeks
1g USD -2 2 Weeks
2g USD -2 2 Weeks
5mg USD 220 2 Weeks
10mg USD 360 2 Weeks
25mg USD 630 2 Weeks
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Synonym: Penicillic acid;

IUPAC/Chemical Name: (Z)-3-methoxy-5-methyl-4-oxohexa-2,5-dienoic acid

InChi Key: VOUGEZYPVGAPBB-XQRVVYSFSA-N

InChi Code: InChI=1S/C8H10O4/c1-5(2)8(11)6(12-3)4-7(9)10/h4H,1H2,2-3H3,(H,9,10)/b6-4-

SMILES Code: C=C(C)C(/C(OC)=C/C(O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 170.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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11: Casquete R, Rodríguez A, Hernández A, Martín A, Bartolomé T, Córdoba JJ, Córdoba MG. Occurrence of Toxigenic Fungi and Mycotoxins during Smoked Paprika Production. J Food Prot. 2017 Dec;80(12):2068-2077. doi: 10.4315/0362-028X.JFP-17-164. PMID: 29154716.

12: Kim JA, Jeon J, Park SY, Kim KT, Choi G, Nguyen HT, Jeon SJ, Lee HB, Bae CH, Yang HS, Yeo JH, Kim JC, Lee YH, Kim S. Draft Genome Sequence of Aspergillus persii NIBRFGC000004109, Which Has Antibacterial Activity against Plant- Pathogenic Bacteria. Genome Announc. 2017 Sep 21;5(38):e00932-17. doi: 10.1128/genomeA.00932-17. PMID: 28935731; PMCID: PMC5609410.

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14: Guijarro B, Larena I, Melgarejo P, De Cal A. Adaptive conditions and safety of the application of Penicillium frequentans as a biocontrol agent on stone fruit. Int J Food Microbiol. 2017 Aug 2;254:25-35. doi: 10.1016/j.ijfoodmicro.2017.05.004. Epub 2017 May 8. PMID: 28511111.

15: Phainuphong P, Rukachaisirikul V, Tadpetch K, Sukpondma Y, Saithong S, Phongpaichit S, Preedanon S, Sakayaroj J. γ-Butenolide and furanone derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178. Phytochemistry. 2017 May;137:165-173. doi: 10.1016/j.phytochem.2017.02.008. Epub 2017 Feb 20. PMID: 28228227.

16: Oh SY, Cedergreen N, Yiannikouris A, Swamy HV, Karrow NA. Assessing interactions of binary mixtures of Penicillium mycotoxins (PMs) by using a bovine macrophage cell line (BoMacs). Toxicol Appl Pharmacol. 2017 Mar 1;318:33-40. doi: 10.1016/j.taap.2017.01.015. Epub 2017 Jan 24. PMID: 28130037.

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19: Hallas-Møller M, Nielsen KF, Frisvad JC. Production of the Fusarium Mycotoxin Moniliformin by Penicillium melanoconidium. J Agric Food Chem. 2016 Jun 8;64(22):4505-10. doi: 10.1021/acs.jafc.6b00298. Epub 2016 May 31. PMID: 27195914.

20: Nguyen HT, Yu NH, Jeon SJ, Lee HW, Bae CH, Yeo JH, Lee HB, Kim IS, Park HW, Kim JC. Antibacterial activities of penicillic acid isolated from Aspergillus persii against various plant pathogenic bacteria. Lett Appl Microbiol. 2016 Jun;62(6):488-93. doi: 10.1111/lam.12578. PMID: 27105128.

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