WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H463480
CAS#: 923783-24-8
Description: Plk1 PBD-IN-143 is a novel Inhibitor of the Polo-Box Domain of Polo-like Kinase 1 (Plk1 PBD).
Hodoodo Cat#: H463480
Name: Plk1 PBD-IN-143
CAS#: 923783-24-8
Chemical Formula: C13H14N4OS
Exact Mass: 274.09
Molecular Weight: 274.342
Elemental Analysis: C, 56.92; H, 5.14; N, 20.42; O, 5.83; S, 11.69
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Synonym: Plk1 PBD-IN-143; Plk1 PBDIN-143; Plk1 PBD IN-143; Plk1 PBD-IN143; Plk1 PBD-IN 143; Plk1 PBDIN143; Plk1 PBD IN 143;
IUPAC/Chemical Name: 1-(methylthio)-4-propyl-[1,2,4]triazolo[4,3-a]quinazolin-5(4H)-one
InChi Key: QCMQLIPWNDLWDB-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H14N4OS/c1-3-8-16-11(18)9-6-4-5-7-10(9)17-12(16)14-15-13(17)19-2/h4-7H,3,8H2,1-2H3
SMILES Code: CSC1=NN=C2N(CCC)C(C3=CC=CC=C3N21)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 274.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |