WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H463870
CAS#: 155593-75-2
Description: Perphenazine-d4 is intended for use as an internal standard for the quantification of perphenazine by GC- or LC-MS. Perphenazine is a typical antipsychotic. It binds to dopamine D2, α1A-, α2A-, α2B-, and α2C-adrenergic, M3 muscarinic, and histamine H1 receptors, as well as the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7. Perphenazine enhances morphine-induced analgesia in the tail-flick and hot plate tests in rats. It reduces cannibalism in female mice when administered at doses of 2 and 4 mg/kg. Formulations containing perphenazine have been used in the treatment of schizophrenia and psychosis.
Hodoodo Cat#: H463870
Name: Perphenazine-d4
CAS#: 155593-75-2
Chemical Formula: C21H22D4ClN3OS
Exact Mass: 407.17
Molecular Weight: 407.993
Elemental Analysis: C, 61.82; H, 7.41; Cl, 8.69; N, 10.30; O, 3.92; S, 7.86
Synonym: Perphenazine-d4; Perphenazine d4;
IUPAC/Chemical Name: 2-(4-(3-(2-chloro-10H-phenothiazin-10-yl-1,3,7,9-d4)propyl)piperazin-1-yl)ethan-1-ol
InChi Key: RGCVKNLCSQQDEP-WNJORUDBSA-N
InChi Code: InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2/i2D,4D,6D,16D
SMILES Code: OCCN1CCN(CCCN2C3=C(C(Cl)=C(C=C3SC4=CC([2H])=CC([2H])=C42)[2H])[2H])CC1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 407.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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