WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H463882
CAS#: 2410279-82-0 (sodium salt)
Description: Taurodeoxycholic acid-d4 is intended for use as an internal standard for the quantification of taurodeoxycholic acid by GC- or LC-MS. Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid. Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally. Serum levels of taurodeoxycholic acid increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.
Hodoodo Cat#: H463882
Name: Taurodeoxycholic Acid-d4 sodium salt
CAS#: 2410279-82-0 (sodium salt)
Chemical Formula: C26H40D4NNaO6S
Exact Mass: 525.30
Molecular Weight: 525.713
Elemental Analysis: C, 59.40; H, 9.20; N, 2.66; Na, 4.37; O, 18.26; S, 6.10
Synonym: Taurodeoxycholic Acid-d4 sodium salt; Taurodeoxycholic Acid d4 sodium salt; Sodium Taurodeoxycholate-d4; Sodium Taurodeoxycholate d4; TDCA-d4; TDCA d4;
IUPAC/Chemical Name: sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl-2,2,4,4-d4)pentanamido)ethane-1-sulfonate
InChi Key: YXHRQQJFKOHLAP-YPYHFUETSA-M
InChi Code: InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1/i10D2,14D2;
SMILES Code: [H][C@@]12[C@@]([H])(CC[C@@]3(C([2H])([C@@H](C([2H])(C[C@@]32C)[2H])O)[2H])[H])[C@@]([H])([C@@]4([C@H](C1)O)C)CC[C@@]4([C@@H](CCC(NCCS(=O)([O-])=O)=O)C)[H].[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 525.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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