WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H413367
CAS#: 166981-11-9
Description: CT 2576 is an inhibitor of phospholipid signaling, suppresses constitutive and induced expression of human immunodeficiency virus
Hodoodo Cat#: H413367
Name: CT 2576
CAS#: 166981-11-9
Chemical Formula: C26H47N5O3
Exact Mass: 477.37
Molecular Weight: 477.690
Elemental Analysis: C, 65.37; H, 9.92; N, 14.66; O, 10.05
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Synonym: CT 2576; CT-2576; CT2576
IUPAC/Chemical Name: 1H-Purine-2,6-dione, 3,7-dihydro-1-(10-hydroxy-11-(octylamino)undecyl)-3,7-dimethyl-
InChi Key: BDKVACCVHNPPIG-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H47N5O3/c1-4-5-6-7-12-15-18-27-20-22(32)17-14-11-9-8-10-13-16-19-31-25(33)23-24(28-21-29(23)2)30(3)26(31)34/h21-22,27,32H,4-20H2,1-3H3
SMILES Code: O=C(N1CCCCCCCCCC(O)CNCCCCCCCC)N(C)C2=C(N(C)C=N2)C1=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 477.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Leung DW, Peterson PK, Weeks R, Gekker G, Chao CC, Kaplan AH, Balantac N, Tompkins C, Underiner GE, Bursten S, et al. CT-2576, an inhibitor of phospholipid signaling, suppresses constitutive and induced expression of human immunodeficiency virus. Proc Natl Acad Sci U S A. 1995 May 23;92(11):4813-7. doi: 10.1073/pnas.92.11.4813. PMID: 7761405; PMCID: PMC41797.
2: Wasik MA, Nowak I, Zhang Q, Shaw LM. Suppression of proliferation and phosphorylation of Jak3 and STAT5 in malignant T-cell lymphoma cells by derivatives of octylamino-undecyl-dimethylxanthine. Leuk Lymphoma. 1998 Feb;28(5-6):551-60. doi: 10.3109/10428199809058363. PMID: 9613985.