Cyanophos
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H413429

CAS#: 2636-26-2

Description: Cyanophos is a cholinesterase inhibitor used as an insecticide and avicide; for example, against rice stem borers and house flies. It is part of the chemical class of organophosphorus compounds, and is a yellow to reddish-yellow transparent liquid.

Chemical Structure

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Cyanophos
CAS# 2636-26-2
Instruction

Theoretical Analysis

Hodoodo Cat#: H413429
Name: Cyanophos
CAS#: 2636-26-2
Chemical Formula: C9H10NO3PS
Exact Mass: 243.01
Molecular Weight: 243.220
Elemental Analysis: C, 44.45; H, 4.14; N, 5.76; O, 19.73; P, 12.74; S, 13.18

Price and Availability

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25mg USD 550 2 Weeks
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Synonym: Cyanophos; HSDB6427; HSDB-6427; HSDB 6427

IUPAC/Chemical Name: Phosphorothioic acid, O,O-dimethyl ester, O-ester with p-hydroxybenzonitrile

InChi Key: SCKHCCSZFPSHGR-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H10NO3PS/c1-11-14(15,12-2)13-9-5-3-8(7-10)4-6-9/h3-6H,1-2H3

SMILES Code: N#CC1=CC=C(OP(OC)(OC)=S)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 100.00

Preparing Stock Solutions

The following data is based on the product molecular weight 243.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Romeh AA. Phytoremediation of cyanophos insecticide by Plantago major L. in water. J Environ Health Sci Eng. 2014 Jan 21;12(1):38. doi: 10.1186/2052-336X-12-38. PMID: 24447385; PMCID: PMC3899885.

2: Ali Romeh A. Enhancing agents for phytoremediation of soil contaminated by cyanophos. Ecotoxicol Environ Saf. 2015 Jul;117:124-31. doi: 10.1016/j.ecoenv.2015.03.029. Epub 2015 Apr 3. PMID: 25847752.

3: Mullié WC, Diallo AO, Gadji B, Ndiaye MD. Environmental hazards of mobile ground spraying with cyanophos and fenthion for quelea control in Senegal. Ecotoxicol Environ Saf. 1999 May;43(1):1-10. doi: 10.1006/eesa.1998.1744. PMID: 10330314.

4: Katami T, Nakamura M, Yasuhara A, Shibamoto T. Migration of organophosphorus insecticides cyanophos and prothiofos residues from impregnated paper bags to Japanese apple-pears (Pyrus pyrifolia nakai cv. Nijisseiki). J Agric Food Chem. 2000 Jun;48(6):2499-501. doi: 10.1021/jf990614r. PMID: 10888575.

5: Menager M, Pilichowski JF, Sarakha M. Reaction pathways for the photodegradation of the organophosphorus cyanophos in aqueous solutions. Photochem Photobiol. 2010 Mar-Apr;86(2):247-54. doi: 10.1111/j.1751-1097.2009.00654.x. Epub 2009 Nov 23. PMID: 19947973.

6: Ageda S, Fuke C, Ihama Y, Miyazaki T. The stability of organophosphorus insecticides in fresh blood. Leg Med (Tokyo). 2006 May;8(3):144-9. doi: 10.1016/j.legalmed.2005.12.003. Epub 2006 Mar 3. PMID: 16517205.

7: Inoue S, Saito T, Mase H, Suzuki Y, Takazawa K, Yamamoto I, Inokuchi S. Rapid simultaneous determination for organophosphorus pesticides in human serum by LC- MS. J Pharm Biomed Anal. 2007 May 9;44(1):258-64. doi: 10.1016/j.jpba.2007.01.036. Epub 2007 Jan 30. PMID: 17337150.

8: Cisse BS, Gras G. Contamination de la canne à sucre par deux avicides: le fenthion et le cyanophos. Evaluation des résidus dans le jus de canne transformé en sucre [Contamination of sugar cane by 2 bird poisons: fenthion and cyanophos. Evaluation of residues in sugar cane juice transformed into sugar]. Dakar Med. 1984;29(2):383-90. French. PMID: 6571259.

9: Hua X, Liu X, Shi H, Wang Y, Kim HJ, Gee SJ, Wang M, Liu F, Hammock BD. Development of a heterologous enzyme-linked immunosorbent assay for organophosphorus pesticides with phage-borne peptide. RSC Adv. 2014 Jan 1;4(80):42445-42453. doi: 10.1039/C4RA07059C. PMID: 26290688; PMCID: PMC4539265.

10: Xu ZL, Deng H, Lei HT, Jiang YM, Campbell K, Shen YD, Yang JY, Wang H, Sun YM. Development of a broad-specificity monoclonal antibody-based immunoaffinity chromatography cleanup for organophosphorus pesticide determination in environmental samples. J Agric Food Chem. 2012 Jun 13;60(23):5847-52. doi: 10.1021/jf300896z. Epub 2012 May 31. PMID: 22612520.