WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H576127
CAS#: 60525-15-7
Description: Zimeldine hydrochloride anhydrous is a serotonin uptake inhibitor that was formerly used for depression but was withdrawn worldwide in September 1983 because of the risk of Guillain-Barre Syndrome associated with its use.
Hodoodo Cat#: H576127
Name: Zimeldine hydrochloride anhydrous
CAS#: 60525-15-7
Chemical Formula: C16H19BrCl2N2
Exact Mass: 388.01
Molecular Weight: 390.150
Elemental Analysis: C, 49.26; H, 4.91; Br, 20.48; Cl, 18.17; N, 7.18
This product is not in stock, which may be available by custom synthesis.
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Synonym: H 102/09; Normud; Zimeldine dihydrochloride; Zimeldine 2HCl; Zimeldine hydrochloride anhydrous
IUPAC/Chemical Name: 2-Propen-1-amine, 3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-, dihydrochloride, (Z)-
InChi Key: CXGURXWCQYHDIR-ULPVBNQHSA-N
InChi Code: InChI=1S/C16H17BrN2.2ClH/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13;;/h3-10,12H,11H2,1-2H3;2*1H/b16-9-;;
SMILES Code: Cl.Cl.CN(C)C\C=C(\c1ccc(Br)cc1)/c2cccnc2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 390.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Seppälä T, Linnoila M. Effects of zimeldine and other antidepressants on skilled performance: a comprehensive review. Acta Psychiatr Scand Suppl. 1983;308:135-40. doi: 10.1111/j.1600-0447.1983.tb11114.x. PMID: 6230887.