WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H464391
CAS#: unknown
Description: QCP02 is a new imaging agent for cancer study.
Hodoodo Cat#: H464391
Name: QCP02
CAS#: unknown
Chemical Formula: C39H53N9O12
Exact Mass: 839.38
Molecular Weight: 839.904
Elemental Analysis: C, 55.77; H, 6.36; N, 15.01; O, 22.86
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Synonym: QCP02; QCP 02; QCP-02;
IUPAC/Chemical Name: 2,2',2''-(10-(1-carboxy-4-((3-((4-((2-((R)-2-cyanopyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)amino)-4-oxobutyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid
InChi Key: OCNCMSLKOGSTHF-XIDOUCRZSA-N
InChi Code: InChI=1S/C39H53N9O12/c40-22-27-3-1-11-48(27)34(50)23-43-38(57)29-8-10-41-31-5-4-28(21-30(29)31)60-20-2-9-42-33(49)7-6-32(39(58)59)47-18-16-45(25-36(53)54)14-12-44(24-35(51)52)13-15-46(17-19-47)26-37(55)56/h4-5,8,10,21,27,32H,1-3,6-7,9,11-20,23-26H2,(H,42,49)(H,43,57)(H,51,52)(H,53,54)(H,55,56)(H,58,59)/t27-,32?/m1/s1
SMILES Code: N#C[C@H]1CCCN1C(CNC(C2=CC=NC3=CC=C(OCCCNC(CCC(C(O)=O)N4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)C=C23)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 839.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Slania SL, Das D, Lisok A, Du Y, Jiang Z, Mease RC, Rowe SP, Nimmagadda S, Yang X, Pomper MG. Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules. J Med Chem. 2021 Mar 17. doi: 10.1021/acs.jmedchem.0c02171. Epub ahead of print. PMID: 33730493.