WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H576437
CAS#: 56335-21-8
Description: Etodroxizine dimaleate is an antihistamine that may be useful in the treatment of insomnia.
Hodoodo Cat#: H576437
Name: Etodroxizine dimaleate
CAS#: 56335-21-8
Chemical Formula: C31H39ClN2O11
Exact Mass: 650.22
Molecular Weight: 651.110
Elemental Analysis: C, 57.19; H, 6.04; Cl, 5.44; N, 4.30; O, 27.03
This product is not in stock, which may be available by custom synthesis.
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Synonym: Drimyl; Etodroxizine dimaleate; Etodroxyzine dimaleate; Hydrochlorbenzethylamine dimaleate; Indunox; Noxadron
IUPAC/Chemical Name: Ethanol, 2-(2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethoxy)-, dimaleate
InChi Key: LCTVSMAEOLQJSR-SPIKMXEPSA-N
InChi Code: InChI=1S/C23H31ClN2O3.2C4H4O4/c24-22-8-6-21(7-9-22)23(20-4-2-1-3-5-20)26-12-10-25(11-13-26)14-16-28-18-19-29-17-15-27;2*5-3(6)1-2-4(7)8/h1-9,23,27H,10-19H2;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
SMILES Code: OCCOCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3.OC(=O)\C=C/C(=O)O.OC(=O)\C=C/C(=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 651.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Kullander NE. A double-blind clinical trial of a new sleep-inducing combination of methaqualone and etodroxizine compared with nitrazepam and placebo. Arzneimittelforschung. 1969 Sep;19(9):1530-2. PMID: 4899293.
2. Wolffgramm J, Lechner J, Coper H. Interaction of two barbiturates and an antihistamine on body temperature and motor performance of mice. Arzneimittelforschung. 1988 Jul;38(7):885-91. PMID: 2905131.