Ureidosuccinic Acid
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Hodoodo CAT#: H464824

CAS#: 923-37-5

Description: Ureidosuccinic acid is an intermediate in the de novo pyrimidine nucleotide biosynthesis pathway. It is formed from aspartate and carbamoyl phosphate via aspartate carbamoyltransferase. Ureidosuccinic acid (350 mg/kg) inhibits antitumor activity and toxicity induced by the aspartate carbamoyltransferase inhibitor N-phosphonacetyl-L-aspartate (PALA) in a murine Lewis lung carcinoma model.

Chemical Structure

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Ureidosuccinic Acid
CAS# 923-37-5
Instruction

Theoretical Analysis

Hodoodo Cat#: H464824
Name: Ureidosuccinic Acid
CAS#: 923-37-5
Chemical Formula: C5H8N2O5
Exact Mass: 176.04
Molecular Weight: 176.130
Elemental Analysis: C, 34.10; H, 4.58; N, 15.91; O, 45.42

Price and Availability

Size Price Availability Quantity
1g USD 250 2 Weeks
5g USD 450 2 Weeks
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Synonym: Ureidosuccinic Acid; Ureidosuccinic-Acid; N-Carbamoylaspartic Acid; N Carbamoylaspartic Acid; N-Carbamoyl-DL-Aspartic Acid; NSC 120033; NSC120033; NSC-120033;

IUPAC/Chemical Name: N-Carbamoyl-DL-aspartic acid

InChi Key: HLKXYZVTANABHZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C5H8N2O5/c6-5(12)7-2(4(10)11)1-3(8)9/h2H,1H2,(H,8,9)(H,10,11)(H3,6,7,12)

SMILES Code: O=C(O)CC(C(O)=O)NC(N)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMF 1.0 2.85
DMSO 1.0 2.85
PBS (pH 7.2) 1.0 2.85

Preparing Stock Solutions

The following data is based on the product molecular weight 176.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shen C, Sun Z, Chen D, Su X, Jiang J, Li G, Lin B, Yan J. Developing urinary metabolomic signatures as early bladder cancer diagnostic markers. OMICS. 2015 Jan;19(1):1-11. doi: 10.1089/omi.2014.0116. PMID: 25562196; PMCID: PMC4281851.

2: Schlumpberger M, Prusiner SB, Herskowitz I. Induction of distinct [URE3] yeast prion strains. Mol Cell Biol. 2001 Oct;21(20):7035-46. doi: 10.1128/MCB.21.20.7035-7046.2001. PMID: 11564886; PMCID: PMC99879.