WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H465206
CAS#: unknown
Description: UCI-50027 is an orally active neuroactive steroid specifically targeted at the gamma-aminobutyric acid(A) receptor (GABAAR).
Hodoodo Cat#: H465206
Name: UCI-50027
CAS#: unknown
Chemical Formula: C24H37NO3
Exact Mass: 387.28
Molecular Weight: 387.564
Elemental Analysis: C, 74.38; H, 9.62; N, 3.61; O, 12.38
This product is not in stock, which may be available by custom synthesis.
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Synonym: UCI-50027; UCI50027; UCI 50027;
IUPAC/Chemical Name: (3R,5S,8R,9S,10S,13S,14S,17S)-17-(5-(hydroxymethyl)isoxazol-3-yl)-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChi Key: WQANJTALVHXWJH-SFXVUFDXSA-N
InChi Code: InChI=1S/C24H37NO3/c1-22(27)10-11-23(2)15(13-22)4-5-17-18-6-7-20(21-12-16(14-26)28-25-21)24(18,3)9-8-19(17)23/h12,15,17-20,26-27H,4-11,13-14H2,1-3H3/t15-,17-,18-,19-,20+,22+,23-,24-/m0/s1
SMILES Code: OCC1=CC([C@H]2CC[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@](C)(O)CC[C@]5(C)[C@@]4([H])CC[C@]23C)=NO1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 387.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Hogenkamp DJ, Tran MB, Yoshimura RF, Johnstone TB, Kanner R, Gee KW. Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid. Psychopharmacology (Berl). 2014 Sep;231(17):3517-24. doi: 10.1007/s00213-014-3494-5. Epub 2014 Feb 28. PMID: 24682501.