WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H465235
CAS#: unknown
Description: DMDHP is a cationic lipid for RNA and vaccine delivery.
Hodoodo Cat#: H465235
Name: DMDHP
CAS#: unknown
Chemical Formula: C36H72INO6
Exact Mass: 741.44
Molecular Weight: 741.878
Elemental Analysis: C, 58.28; H, 9.78; I, 17.11; N, 1.89; O, 12.94
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: DMDHP;
IUPAC/Chemical Name: N,N-bis(2-hydroxyethyl)-N-methyl-2,3-bis(tetradecanoyloxy)propan-1-aminium iodide
InChi Key: AOHONAOXDBVDFG-UHFFFAOYSA-M
InChi Code: InChI=1S/C36H72NO6.HI/c1-4-6-8-10-12-14-16-18-20-22-24-26-35(40)42-33-34(32-37(3,28-30-38)29-31-39)43-36(41)27-25-23-21-19-17-15-13-11-9-7-5-2;/h34,38-39H,4-33H2,1-3H3;1H/q+1;/p-1
SMILES Code: C[N+](CCO)(CC(COC(CCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCC)=O)CCO.[I-]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 741.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Laali KK, Okazaki T, Mitchell RH, Ward TR. Novel annulene dications from methylated [2.2]metacyclophane monoenes and [e]-ring benzannelated dimethyldihydropyrene. J Org Chem. 2001 Aug 10;66(16):5329-32. doi: 10.1021/jo0100594. PMID: 11485451.
2: Bodwell GJ, Bridson JN, Chen SL, Poirier RA. Nonplanar aromatic compounds. 5. A atrategy for the synthesis of cis-10b,10c-dimethyl-10b,10c-dihydropyrenes. First crystal structure of a cis-10b,10c-dimethyl-10b,10c-dihydropyrene. J Am Chem Soc. 2001 May 23;123(20):4704-8. doi: 10.1021/ja002901d. PMID: 11457279.
3: Kulys J. The carbon paste electrode encrusted with a microreactor as glucose biosensor. Biosens Bioelectron. 1999 May 31;14(5):473-9. doi: 10.1016/s0956-5663(99)00026-3. PMID: 10451915.