WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H465254
CAS#: 871258-14-9
Description: DSDMA is a lipid for RNA and vaccine delivery.
Hodoodo Cat#: H465254
Name: DSDMA
CAS#: 871258-14-9
Chemical Formula: C41H85NO2
Exact Mass: 623.66
Molecular Weight: 624.136
Elemental Analysis: C, 78.90; H, 13.73; N, 2.24; O, 5.13
This product is not in stock, which may be available by custom synthesis.
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Synonym: DSDMA;
IUPAC/Chemical Name: N,N-dimethyl-2,3-bis(octadecyloxy)propan-1-amine
InChi Key: JQRHOXPYDFZULQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C41H85NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h41H,5-40H2,1-4H3
SMILES Code: CN(C)CC(COCCCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCCCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 624.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Wei X, Moad G, Muir BW, Rizzardo E, Rosselgong J, Yang W, Thang SH. An arm- first approach to cleavable mikto-arm star polymers by RAFT polymerization. Macromol Rapid Commun. 2014 Apr;35(8):840-5. doi: 10.1002/marc.201300879. Epub 2014 Feb 6. PMID: 24504709.
2: Heyes J, Palmer L, Bremner K, MacLachlan I. Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. J Control Release. 2005 Oct 3;107(2):276-87. doi: 10.1016/j.jconrel.2005.06.014. PMID: 16054724.