WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H465258
CAS#: 1777792-34-3
Description: ATX-2, also known as ATX-002, is a lipid for RNA and vaccine delivery.
Hodoodo Cat#: H465258
Name: ATX-002
CAS#: 1777792-34-3
Chemical Formula: C39H72N2O5S
Exact Mass: 680.52
Molecular Weight: 681.074
Elemental Analysis: C, 68.78; H, 10.66; N, 4.11; O, 11.75; S, 4.71
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: ATX-2; ATX2; ATX 2; ATX-002; ATX 002; ATX002;
IUPAC/Chemical Name: di((Z)-non-2-en-1-yl) 8,8'-((((2-(dimethylamino)ethyl)thio)carbonyl)azanediyl)dioctanoate
InChi Key: RGAIHNZNCGOCLA-ZDSKVHJSSA-N
InChi Code: InChI=1S/C39H72N2O5S/c1-5-7-9-11-13-21-27-34-45-37(42)29-23-17-15-19-25-31-41(39(44)47-36-33-40(3)4)32-26-20-16-18-24-30-38(43)46-35-28-22-14-12-10-8-6-2/h21-22,27-28H,5-20,23-26,29-36H2,1-4H3/b27-21-,28-22-
SMILES Code: CN(CCSC(N(CCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCC(OC/C=C\CCCCCC)=O)=O)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 681.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Stubenvoll MD, Medley JC, Irwin M, Song MH. ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics. PLoS Genet. 2016 Sep 30;12(9):e1006370. doi: 10.1371/journal.pgen.1006370. Erratum in: PLoS Genet. 2016 Dec 27;12 (12 ):e1006519. PMID: 27689799; PMCID: PMC5045193.