WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H414694
CAS#: 76676-34-1 (K+)
Description: Oxprenoate potassium is a synthetic steroidal antimineralocorticoid which was never marketed. The affinities of oxprenoate potassium for the steroid hormone receptors have been reported.
Hodoodo Cat#: H414694
Name: Oxprenoate potassium
CAS#: 76676-34-1 (K+)
Chemical Formula: C25H37KO4
Exact Mass: 440.23
Molecular Weight: 440.670
Elemental Analysis: C, 68.14; H, 8.46; K, 8.87; O, 14.52
Related CAS #: 786592-95-8 (free base); 76676-34-1 (K+)
Synonym: Oxprenoate potassium; RU28318; RU-28318; RU 28318
IUPAC/Chemical Name: Potassium 17-hydroxy-3-oxo-7alpha-propyl-17alpha-pregn-4-ene-21-carboxylate
InChi Key: HXJITUGMCJCKCE-NKTBGYRQSA-M
InChi Code: InChI=1S/C25H38O4.K/c1-4-5-16-14-17-15-18(26)6-10-23(17,2)19-7-11-24(3)20(22(16)19)8-12-25(24,29)13-9-21(27)28;/h15-16,19-20,22,29H,4-14H2,1-3H3,(H,27,28);/q;+1/p-1/t16-,19+,20+,22-,23+,24+,25+;/m1./s1
SMILES Code: C[C@@]12[C@](CCC([O-])=O)(O)CC[C@@]1([H])[C@]3([H])[C@H](CCC)CC4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O.[K+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 440.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Crochemore C, Lu J, Wu Y, Liposits Z, Sousa N, Holsboer F, Almeida OF. Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation. Mol Psychiatry. 2005 Aug;10(8):790-8. doi: 10.1038/sj.mp.4001679. PMID: 15940303.