WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H465339
CAS#: unknown
Description: VYN-00381 is a Novel Potent and Selective Inducible Nitric Oxide Synthase (iNOS) Inhibitor (IC50 = 74 nM) with high BBB permeability (Pe = 19.1 × 10-6 cm/s) for Parkinson's Disease. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to Hodoodo Chemical Nomenclature (https://www.hodoodo.com/page/naming).
Hodoodo Cat#: H465339
Name: VYN-00381
CAS#: unknown
Chemical Formula: C19H15F4NO3
Exact Mass: 381.10
Molecular Weight: 381.327
Elemental Analysis: C, 59.85; H, 3.97; F, 19.93; N, 3.67; O, 12.59
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: VYN-00381; VYN00381; VYN 00381; iNOS-IN-18;
IUPAC/Chemical Name: (S,E)-3-(4-fluorophenyl)-2-(3-(4-(trifluoromethyl)phenyl)acrylamido)propanoic acid
InChi Key: VXTNIOWCDILANK-YKXBDCQTSA-N
InChi Code: InChI=1S/C19H15F4NO3/c20-15-8-3-13(4-9-15)11-16(18(26)27)24-17(25)10-5-12-1-6-14(7-2-12)19(21,22)23/h1-10,16H,11H2,(H,24,25)(H,26,27)/b10-5+/t16-/m0/s1
SMILES Code: O=C(O)[C@@H](NC(/C=C/C1=CC=C(C(F)(F)F)C=C1)=O)CC2=CC=C(F)C=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 381.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |