WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H465466
CAS#: unknown
Description: QC-308 a Heme Oxygenase‑1 Inhibitor.
Hodoodo Cat#: H465466
Name: QC-308
CAS#: unknown
Chemical Formula: C19H18N2O
Exact Mass: 290.14
Molecular Weight: 290.366
Elemental Analysis: C, 78.59; H, 6.25; N, 9.65; O, 5.51
This product is not in stock, which may be available by custom synthesis.
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Synonym: QC-308; QC 308; QC308;
IUPAC/Chemical Name: 1-(1H-imidazol-1-yl)-4,4-diphenylbutan-2-one
InChi Key: SRAWFXXOZVYZRX-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H18N2O/c22-18(14-21-12-11-20-15-21)13-19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-12,15,19H,13-14H2
SMILES Code: O=C(CN1C=CN=C1)CC(C2=CC=CC=C2)C3=CC=CC=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 290.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Rahman MN, Vlahakis JZ, Vukomanovic D, Lee W, Szarek WA, Nakatsu K, Jia Z. A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition. PLoS One. 2012;7(1):e29514. doi: 10.1371/journal.pone.0029514. Epub 2012 Jan 19. PMID: 22276118; PMCID: PMC3261875.