WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H466153
CAS#: 18684-55-4
Description: 7-OCA, also known as 7-Oxocallitrisic acid, is a natural lipid metabolism regulator.
Hodoodo Cat#: H466153
Name: 7-OCA
CAS#: 18684-55-4
Chemical Formula: C20H26O3
Exact Mass: 314.19
Molecular Weight: 314.425
Elemental Analysis: C, 76.40; H, 8.34; O, 15.27
This product is not in stock, which may be available by custom synthesis.
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Synonym: 7-OCA; 7OCA; 7 OCA; 7-Oxocallitrisic acid; 7 Oxocallitrisic acid; 7-Ketodehydroabietic acid; 7 Ketodehydroabietic acid;
IUPAC/Chemical Name: (1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
InChi Key: MSWJSDLNPCSSNW-MISYRCLQSA-N
InChi Code: InChI=1S/C20H26O3/c1-12(2)13-6-7-15-14(10-13)16(21)11-17-19(15,3)8-5-9-20(17,4)18(22)23/h6-7,10,12,17H,5,8-9,11H2,1-4H3,(H,22,23)/t17-,19-,20-/m1/s1
SMILES Code: O=C([C@]1(C)CCC[C@]2(C)C3=C(C(C[C@@]12[H])=O)C=C(C(C)C)C=C3)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 314.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Jiang J, Liu Y, Yang S, Peng H, Liu J, Cheng YX, Li N. Photoaffinity-Based Chemical Proteomics Reveals 7-Oxocallitrisic Acid Targets CPT1A to Trigger Lipogenesis Inhibition. ACS Med Chem Lett. 2021 Nov 2;12(12):1905-1911. doi: 10.1021/acsmedchemlett.1c00316. PMID: 34917253; PMCID: PMC8667300.
2: Lee S, Choi E, Yang SM, Ryoo R, Moon E, Kim SH, Kim KH. Bioactive compounds from sclerotia extract of Poria cocos that control adipocyte and osteoblast differentiation. Bioorg Chem. 2018 Dec;81:27-34. doi: 10.1016/j.bioorg.2018.07.031. Epub 2018 Jul 31. PMID: 30092384.
3: Yang XW, Feng L, Li SM, Liu XH, Li YL, Wu L, Shen YH, Tian JM, Zhang X, Liu XR, Wang N, Liu Y, Zhang WD. Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. Bioorg Med Chem. 2010 Jan 15;18(2):744-54. doi: 10.1016/j.bmc.2009.11.055. Epub 2009 Dec 3. PMID: 20022253.
