F-1322

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H578009

CAS#: 143964-80-1

Description: F-1322 is an anti-asthmatic agent.

Chemical Structure

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F-1322
CAS# 143964-80-1
Instruction

Theoretical Analysis

Hodoodo Cat#: H578009
Name: F-1322
CAS#: 143964-80-1
Chemical Formula: C37H37N3O4
Exact Mass: 587.28
Molecular Weight: 587.720
Elemental Analysis: C, 75.62; H, 6.35; N, 7.15; O, 10.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: F-1322; F 1322; F1322; NC-2000; NC 2000; NC2000; SOA 132; SOA-132; SOA132

IUPAC/Chemical Name: N-(2-(4-(Diphenylmethoxy)-1-piperidinyl)ethyl)-3-hydroxy-5-(3-pyridinylmethoxy)-2-naphthalenecarboxamide

InChi Key: ZBOYHAZRFJBUEL-UHFFFAOYSA-N

InChi Code: 1S/C37H37N3O4/c41-34-24-32-30(14-7-15-35(32)43-26-27-9-8-18-38-25-27)23-33(34)37(42)39-19-22-40-20-16-31(17-21-40)44-36(28-10-3-1-4-11-28)29-12-5-2-6-13-29/h1-15,18,23-25,31,36,41H,16-17,19-22,26H2,(H,39,42)

SMILES Code: Oc1cc2c(OCc3cccnc3)cccc2cc1C(=O)NCCN4CCC(CC4)OC(c5ccccc5)c6ccccc6

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 587.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Mochizuki A, Tamura N, Yatabe Y, Onodera S, Hiruma T, Inaba N, Kusunoki J, Tomioka H. Suppressive effects of F-1322 on the antigen-induced late asthmatic response and pulmonary eosinophilia in guinea pigs. Eur J Pharmacol. 2001 Oct 26;430(1):123-33. doi: 10.1016/s0014-2999(01)01364-4. PMID: 11698072.

2. Lee B, Takasaki K, Mochizuki A, Tamura N, Higashide Y, Yamaura T. [Pharmacological profiles of F-1322, a novel anti-asthmatic agent. (1). Mechanisms of action]. Nihon Yakurigaku Zasshi. 1995 Jul;106(1):31-40. Japanese. doi: 10.1254/fpj.106.31. PMID: 7590521.

3. Mochizuki A, Lee B, Shibata M, Kasai M, Tanaka T, Iwamoto I. Inhibitory effect of F-1322 on allergic eosinophil infiltration in airways. Eur J Pharmacol. 1998 Feb 19;343(2-3):233-7. doi: 10.1016/s0014-2999(97)01534-3. PMID: 9570472.