NIP-502

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Hodoodo CAT#: H578192

CAS#: 108616-42-8

Description: NIP-502 is a pyridazinone derivative that has been shown to inhibit antigen-induced bronchial responses and allergic reactions.


Chemical Structure

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NIP-502
CAS# 108616-42-8

Theoretical Analysis

Hodoodo Cat#: H578192
Name: NIP-502
CAS#: 108616-42-8
Chemical Formula: C14H16ClN3O3
Exact Mass: 309.09
Molecular Weight: 309.750
Elemental Analysis: C, 54.29; H, 5.21; Cl, 11.44; N, 13.57; O, 15.50

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: NIP-502; NIP 502; NIP502

IUPAC/Chemical Name: 3(2H)-Pyridazinone, 4-chloro-5-(((3-ethoxy-4-methoxyphenyl)methyl)amino)-

InChi Key: MLZKFBZEYADEIN-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H16ClN3O3/c1-3-21-12-6-9(4-5-11(12)20-2)7-16-10-8-17-18-14(19)13(10)15/h4-6,8H,3,7H2,1-2H3,(H2,16,18,19)

SMILES Code: CCOc1cc(CNC2=C(Cl)C(=O)NN=C2)ccc1OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 309.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Yamamoto A, Iwama T, Takeda H, Nagai H. Effects of NIP-502 on antigen-induced bronchial responses and allergic reactions in animal models. Jpn J Pharmacol. 1995 May;68(1):47-55. doi: 10.1254/jjp.68.47. PMID: 7494382.