WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H578192
CAS#: 108616-42-8
Description: NIP-502 is a pyridazinone derivative that has been shown to inhibit antigen-induced bronchial responses and allergic reactions.
Hodoodo Cat#: H578192
Name: NIP-502
CAS#: 108616-42-8
Chemical Formula: C14H16ClN3O3
Exact Mass: 309.09
Molecular Weight: 309.750
Elemental Analysis: C, 54.29; H, 5.21; Cl, 11.44; N, 13.57; O, 15.50
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Synonym: NIP-502; NIP 502; NIP502
IUPAC/Chemical Name: 3(2H)-Pyridazinone, 4-chloro-5-(((3-ethoxy-4-methoxyphenyl)methyl)amino)-
InChi Key: MLZKFBZEYADEIN-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H16ClN3O3/c1-3-21-12-6-9(4-5-11(12)20-2)7-16-10-8-17-18-14(19)13(10)15/h4-6,8H,3,7H2,1-2H3,(H2,16,18,19)
SMILES Code: CCOc1cc(CNC2=C(Cl)C(=O)NN=C2)ccc1OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 309.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Yamamoto A, Iwama T, Takeda H, Nagai H. Effects of NIP-502 on antigen-induced bronchial responses and allergic reactions in animal models. Jpn J Pharmacol. 1995 May;68(1):47-55. doi: 10.1254/jjp.68.47. PMID: 7494382.