WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H112009
CAS#: 38965-51-4
Description: Eriodictyol 7-O-glucoside is a flavanone glucoside that has been found in V. coloratum and has diverse biological activities. It scavenges hydroxyl and superoxide anion radicals in cell-free assays (IC50s = 0.28 and 0.3 mM, respectively). Eriodictyol 7-O-glucoside activates nuclear factor E2-related factor 2 (Nrf2) in a reporter assay. It protects against cytotoxicity induced by cisplatin in human renal mesangial cells (HRMCs), but not A549 lung or MDA-MB-231 breast cancer cells, when used at a concentration of 80 µM. Eriodictyol 7-O-glucoside (30 mg/kg) attenuates neurological deficits and reduces infarct volume in a rat model of cerebral ischemia induced by middle cerebral artery occlusion (MCAO).
Hodoodo Cat#: H112009
Name: Eriodictyol 7-O-glucoside
CAS#: 38965-51-4
Chemical Formula: C21H22O11
Exact Mass: 450.12
Molecular Weight: 450.400
Elemental Analysis: C, 56.00; H, 4.92; O, 39.07
Synonym: 7-O-β-D-Glucopyranosyl-eriodictyol; (2S)-Eriodictyol 7-O-β-D-glucopyranoside
IUPAC/Chemical Name: (S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one
InChi Key: RAFHNDRXYHOLSH-SFTVRKLSSA-N
InChi Code: InChI=1S/C21H22O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-5,14,16,18-25,27-29H,6-7H2/t14-,16+,18+,19-,20+,21+/m0/s1
SMILES Code: OC1=CC([C@@H](O2)CC(C(C2=C3)=C(O)C=C3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=O)=CC=C1O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.5 | 10.00 |
The following data is based on the product molecular weight 450.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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