WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H112064
CAS#: 112-79-8
Description: Elaidic acid is a monounsaturated trans fatty acid and the 9-trans isomer of oleic acid and reduces HHT and HETE formation and induces apoptosis in human umbilical vein endothelial cells.
Hodoodo Cat#: H112064
Name: Elaidic Acid
CAS#: 112-79-8
Chemical Formula: C18H34O2
Exact Mass: 282.26
Molecular Weight: 282.470
Elemental Analysis: C, 76.54; H, 12.13; O, 11.33
Synonym: Elaidic Acid; C18:1(9E); 9(E)-Oleic Acid; trans-Oleic Acid; C18:1 9E; 9(E)Oleic Acid; transOleic Acid; 9(E) Oleic Acid; trans Oleic Acid
IUPAC/Chemical Name: (E)-octadec-9-enoic acid
InChi Key: ZQPPMHVWECSIRJ-MDZDMXLPSA-N
InChi Code: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9+
SMILES Code: CCCCCCCC/C=C/CCCCCCCC(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 282.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Ma WW, Zhao L, Yuan LH, Yu HL, Wang H, Gong XY, Wei F, Xiao R. Elaidic acid induces cell apoptosis through induction of ROS accumulation and endoplasmic reticulum stress in SH‑SY5Y cells. Mol Med Rep. 2017 Dec;16(6):9337-9346. doi: 10.3892/mmr.2017.7830. Epub 2017 Oct 19. PMID: 29152653; PMCID: PMC5779995.
2: Hirata Y, Nada Y, Yamada Y, Toyama T, Fukunaga K, Hwang GW, Noguchi T, Matsuzawa A. Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X7-ROS-ASK1-p38 Axis in Microglial Cell Lines. Biol Pharm Bull. 2020;43(10):1562-1569. doi: 10.1248/bpb.b20-00409. PMID: 32999166.