WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H112107
CAS#: 23313-21-5
Description: Emodin 8-glucoside inhibits the activities of rat lens aldose reductase and human DNA topoisomerase II (IC50s = 14.4 and 66 μM, respectively, in cell-free assays) and promotes the proliferation and differentiation of mouse MC3T3-E1 osteoblastic cells.
Hodoodo Cat#: H112107
Name: Emodin 8-glucoside
CAS#: 23313-21-5
Chemical Formula: C21H20O10
Exact Mass: 432.11
Molecular Weight: 432.380
Elemental Analysis: C, 58.34; H, 4.66; O, 37.00
Synonym: Emodin 8-glucoside; Emodin 8-O-β-D-glucopyranoside; Emodin 8-β-D-glucoside; NSC 257449; NSC257449; NSC-257449; Emodin 8glucoside; Emodin 8 glucoside
IUPAC/Chemical Name: 1,6-dihydroxy-3-methyl-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)anthracene-9,10-dione
InChi Key: HSWIRQIYASIOBE-JNHRPPPUSA-N
InChi Code: InChI=1S/C21H20O10/c1-7-2-9-14(11(24)3-7)18(27)15-10(16(9)25)4-8(23)5-12(15)30-21-20(29)19(28)17(26)13(6-22)31-21/h2-5,13,17,19-24,26,28-29H,6H2,1H3/t13-,17-,19+,20-,21-/m1/s1
SMILES Code: O=C(C1=CC(O)=CC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=C13)C4=CC(C)=CC(O)=C4C3=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMF | 25.0 | 57.82 | |
DMSO | 30.0 | 69.38 |
The following data is based on the product molecular weight 432.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |