WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: 125295
CAS#: 1225-01-0
Description: 19-norandrosterone is a 17-oxo steroid. It has a role as a metabolite. It derives from a hydride of an estrane.
Hodoodo Cat#: 125295
Name: 19-Norandrosterone
CAS#: 1225-01-0
Chemical Formula: C18H28O2
Exact Mass: 276.21
Molecular Weight: 276.420
Elemental Analysis: C, 78.21; H, 10.21; O, 11.58
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Synonym: 19-Norandrosterone; 1225-01-0; 19-Noreoiandrosterone; 5alpha-Estran-3alpha-ol-17-one; 3alpha-hydroxy-5alpha-estran-17-one
IUPAC/Chemical Name: (3R,5S,8R,9R,10S,13S,14S)-3-hydroxy-13-methyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-17-one
InChi Key: UOUIARGWRPHDBX-CQZDKXCPSA-N
InChi Code: InChI=1S/C18H28O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h11-16,19H,2-10H2,1H3/t11-,12+,13-,14+,15+,16-,18-/m0/s1
SMILES Code: O=C1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)CC[C@]4([H])[C@@]3([H])CC[C@]12C
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 276.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Ayotte C. Significance of 19-norandrosterone in athletes' urine samples. Br J
Sports Med. 2006 Jul;40 Suppl 1(Suppl 1):i25-9. doi: 10.1136/bjsm.2006.028027.
PMID: 16799098; PMCID: PMC2657496.
2: Hülsemann F, Fußhöller G, Lehn C, Thevis M. Excretion of 19-norandrosterone
after consumption of boar meat. Drug Test Anal. 2020 Nov;12(11-12):1581-1586.
doi: 10.1002/dta.2958. Epub 2020 Nov 14. PMID: 33125835.
3: Iannella L, Colamonici C, Curcio D, Botrè F, de la Torre X. Detecting the
abuse of 19-norsteroids in doping controls: A new gas chromatography coupled to
isotope ratio mass spectrometry method for the analysis of 19-norandrosterone
and 19-noretiocholanolone. Drug Test Anal. 2021 Apr;13(4):770-784. doi:
10.1002/dta.2985. Epub 2020 Dec 8. PMID: 33242373.
4: Strahm E, Baume N, Mangin P, Saugy M, Ayotte C, Saudan C. Profiling of
19-norandrosterone sulfate and glucuronide in human urine: implications in
athlete's drug testing. Steroids. 2009 Mar;74(3):359-64. doi:
10.1016/j.steroids.2008.11.005. Epub 2008 Nov 13. PMID: 19056413.
5: Le Bizec B, Monteau F, Gaudin I, André F. Evidence for the presence of
endogenous 19-norandrosterone in human urine. J Chromatogr B Biomed Sci Appl.
1999 Feb 19;723(1-2):157-72. doi: 10.1016/s0378-4347(98)00541-6. PMID: 10080643.
6: Tseng YL, Kuo FH, Sun KH. Quantification and profiling of 19-norandrosterone
and 19-noretiocholanolone in human urine after consumption of a nutritional
supplement and norsteroids. J Anal Toxicol. 2005 Mar;29(2):124-34. doi:
10.1093/jat/29.2.124. PMID: 15902981.
7: Björkhem I, Ek H. Detection and quantitation of 19-norandrosterone in urine
by isotope dilution-mass spectrometry. J Steroid Biochem. 1982 Oct;17(4):447-51.
doi: 10.1016/0022-4731(82)90640-9. PMID: 7132356.
8: De Wasch K, Le Bizec B, De Brabander H, André F, Impens S. Consequence of
boar edible tissue consumption on urinary profiles of nandrolone metabolites.
II. Identification and quantification of 19-norsteroids responsible for
19-norandrosterone and 19-noretiocholanolone excretion in human urine. Rapid
Commun Mass Spectrom. 2001;15(16):1442-7. doi: 10.1002/rcm.391. PMID: 11507757.
9: Palermo A, Alessi B, Botrè F, de la Torre X, Fiacco I, Mazzarino M. In vitro
evaluation of the effects of anti-fungals, benzodiazepines and non-steroidal
anti-inflammatory drugs on the glucuronidation of 19-norandrosterone:
implications on doping control analysis. Drug Test Anal. 2016 Sep;8(9):930-9.
doi: 10.1002/dta.1897. Epub 2015 Oct 20. PMID: 26480899.