WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H524131
CAS#: 42228-92-2
Description: Acivicin is an inhibitor of gamma-glutamyl transferase. It is a potent antineoplastic agent. Acivicin interferes with glutamate metabolism and inhibits glutamate dependent synthesis of enzymes, and is thereby potentially helpful in treatment of solid tumors.
Hodoodo Cat#: H524131
Name: Acivicin
CAS#: 42228-92-2
Chemical Formula: C5H7ClN2O3
Exact Mass: 178.01
Molecular Weight: 178.570
Elemental Analysis: C, 33.63; H, 3.95; Cl, 19.85; N, 15.69; O, 26.88
Synonym: Acivicin; Antibiotic AT-125; NSC 163501; U 42126;
IUPAC/Chemical Name: (2S)-Amino[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]ethanoic acid
InChi Key: QAWIHIJWNYOLBE-OKKQSCSOSA-N
InChi Code: InChI=1S/C5H7ClN2O3/c6-3-1-2(11-8-3)4(7)5(9)10/h2,4H,1,7H2,(H,9,10)/t2-,4-/m0/s1
SMILES Code: O=C(O)[C@@H](N)[C@@H]1CC(Cl)=NO1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 178.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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