WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H524153
CAS#: 2080306-27-8 (HCl)
Description: FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.
Hodoodo Cat#: H524153
Name: FFN200 HCl
CAS#: 2080306-27-8 (HCl)
Chemical Formula: C11H14Cl2N2O
Exact Mass: 0.00
Molecular Weight: 277.145
Elemental Analysis: C, 47.67; H, 5.09; Cl, 25.58; N, 10.11; O, 11.55
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Related CAS #: 2080306-26-7 (free base) 2080306-27-8 (2HCl)
Synonym: FFN200 HCl; FFN200 dihydrochloride; FFN200; FFN-200; FFN 200.
IUPAC/Chemical Name: 4-(2-Aminoethyl)-7-amino-2H-1-benzopyran-2-one dihydrochloride
InChi Key: YNQXRSNAOWBGLD-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H12N2O2.2ClH/c12-4-3-7-5-11(14)15-10-6-8(13)1-2-9(7)10;;/h1-2,5-6H,3-4,12-13H2;2*1H
SMILES Code: O=C1C=C(CCN)C2=CC=C(N)C=C2O1.[H]Cl.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 277.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Pereira DB, Schmitz Y, Mészáros J, Merchant P, Hu G, Li S, Henke A,
Lizardi-Ortiz JE, Karpowicz RJ Jr, Morgenstern TJ, Sonders MS, Kanter E,
Rodriguez PC, Mosharov EV, Sames D, Sulzer D. Fluorescent false neurotransmitter
reveals functionally silent dopamine vesicle clusters in the striatum. Nat
Neurosci. 2016 Apr;19(4):578-86. doi: 10.1038/nn.4252. PubMed PMID: 26900925;
PubMed Central PMCID: PMC4853199.