WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H524265
CAS#: 80712-94-3
Description: AS-701 is a Li+ selective ionophore in the therapy of manic-depressive illness.
Hodoodo Cat#: H524265
Name: AS 701
CAS#: 80712-94-3
Chemical Formula: C31H62N2O6
Exact Mass: 558.46
Molecular Weight: 558.840
Elemental Analysis: C, 66.63; H, 11.18; N, 5.01; O, 17.18
This product is not in stock, which may be available by custom synthesis.
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Synonym: AS 701; AS701; AS-701;
IUPAC/Chemical Name: 3,9,13-Trioxa-6-azapentadecan-15-amide, N-(2-ethoxyethyl)-N,6-diheptyl-11,11-dimethyl-7-oxo-
InChi Key: HHEANNFOQVQFBO-UHFFFAOYSA-N
InChi Code: InChI=1S/C31H62N2O6/c1-7-11-13-15-17-19-32(21-23-36-9-3)29(34)25-38-27-31(5,6)28-39-26-30(35)33(22-24-37-10-4)20-18-16-14-12-8-2/h7-28H2,1-6H3
SMILES Code: CCCCCCCN(CCOCC)C(=O)COCC(C)(C)COCC(=O)N(CCCCCCC)CCOCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 558.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Asliyuce S, Uzun L, Rad AY, Unal S, Say R, Denizli A. Molecular imprinting based composite cryogel membranes for purification of anti-hepatitis B surface antibody by fast protein liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 15;889-890:95-102. doi: 10.1016/j.jchromb.2012.02.001. Epub 2012 Feb 9. PubMed PMID: 22382092.
2: Okuda T, Iwase T, Ueda H, Suda Y, Tanaka S, Dokiya Y, Fushimi K, Hosoe M. The impact of volcanic gases from Miyake island on the chemical constituents in precipitation in the Tokyo metropolitan area. Sci Total Environ. 2005 Apr 1;341(1-3):185-97. Epub 2004 Nov 23. PubMed PMID: 15833251.
3: Goldshlegger R, Karlish SJ, Rephaeli A, Stein WD. The effect of membrane potential on the mammalian sodium-potassium pump reconstituted into phospholipid vesicles. J Physiol. 1987 Jun;387:331-55. PubMed PMID: 2443682; PubMed Central PMCID: PMC1192507.
4: Margalit R, Shanzer A. A study of Li+-selective permeation through lipid bilayer membranes mediated by a new ionophore (AS701). Biochim Biophys Acta. 1981 Dec 7;649(2):441-8. PubMed PMID: 7317408.
