WAY 150138

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H526572

CAS#: 273388-09-3

Description: WAY 150138 can cause the inhibition of the herpes simplex virus.

Chemical Structure

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WAY 150138
CAS# 273388-09-3
Instruction

Theoretical Analysis

Hodoodo Cat#: H526572
Name: WAY 150138
CAS#: 273388-09-3
Chemical Formula: C22H18Cl2FN3O3S
Exact Mass: 493.04
Molecular Weight: 494.362
Elemental Analysis: C, 53.45; H, 3.67; Cl, 14.34; F, 3.84; N, 8.50; O, 9.71; S, 6.49

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: WAY 150138; WAY150138; WAY-150138

IUPAC/Chemical Name: N-(3-chloro-4-(3-(5-chloro-2,4-dimethoxyphenyl)thioureido)phenyl)-2-fluorobenzamide

InChi Key: NPZHFWHOVNAVCF-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H18Cl2FN3O3S/c1-30-19-11-20(31-2)18(10-15(19)24)28-22(32)27-17-8-7-12(9-14(17)23)26-21(29)13-5-3-4-6-16(13)25/h3-11H,1-2H3,(H,26,29)(H2,27,28,32)

SMILES Code: O=C(NC1=CC=C(NC(NC2=CC(Cl)=C(OC)C=C2OC)=S)C(Cl)=C1)C3=CC=CC=C3F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 494.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Newcomb WW, Brown JC. Inhibition of herpes simplex virus replication by WAY-150138: assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation. J Virol. 2002 Oct;76(19):10084-8. PubMed PMID: 12208991; PubMed Central PMCID: PMC136520.

2: Newcomb WW, Thomsen DR, Homa FL, Brown JC. Assembly of the herpes simplex virus capsid: identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids. J Virol. 2003 Sep;77(18):9862-71. PubMed PMID: 12941896; PubMed Central PMCID: PMC224603.

3: Pesola JM, Zhu J, Knipe DM, Coen DM. Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production. J Virol. 2005 Dec;79(23):14516-25. Erratum in: J Virol. 2006 Jun;80(12):6196. PubMed PMID: 16282451; PubMed Central PMCID: PMC1287588.