WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H524809
CAS#: 96865-21-3
Description: CP 65,207 is a new broad-spectrum penem antimicrobial agent that is a 1:1 mixture of two stereoisomers.
Hodoodo Cat#: H524809
Name: CP 65207
CAS#: 96865-21-3
Chemical Formula: C12H14NNaO5S3
Exact Mass: 0.00
Molecular Weight: 371.430
Elemental Analysis: C, 38.80; H, 3.80; N, 3.77; Na, 6.19; O, 21.54; S, 25.90
This product is not in stock, which may be available by custom synthesis.
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Synonym: CP 65207; CP-65207 ; CP65207;CP 81054.
IUPAC/Chemical Name: 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-((tetrahydro-3-thienyl)thio)-, S-oxide, monosodium salt, (5R-(5alpha,6alpha(R*)))-
InChi Key: MRHMJKHFABHUKB-VASRXWSJSA-M
InChi Code: InChI=1S/C12H15NO5S3.Na/c1-5(14)7-9(15)13-8(11(16)17)12(20-10(7)13)19-6-2-3-21(18)4-6;/h5-7,10,14H,2-4H2,1H3,(H,16,17);/q;+1/p-1/t5-,6?,7+,10-,21?;/m1./s1
SMILES Code: C[C@H]([C@@H]1[C@@H]2N(C1=O)C(=C(S2)SC3CCS(=O)C3)C(=O)[O-])O.[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 371.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Foulds G, Knirsch AK, Lazar JD, Tensfelt TG, Gerber N. Pharmacokinetics of the penem CP-65,207 and its separate stereoisomers in humans. Antimicrob Agents Chemother. 1991 Apr;35(4):665-71. Erratum in: Antimicrob Agents Chemother 1991 Aug;35(8):1695. PubMed PMID: 2069372; PubMed Central PMCID: PMC245076.
2: Gootz T, Girard D, Schelkley W, Tensfeldt T, Foulds G, Kellogg M, Stam J, Campbell B, Jasys J, Kelbaugh P, et al. Pharmacokinetic studies in animals of a new parenteral penem CP-65,207 and its oral prodrug ester. J Antibiot (Tokyo). 1990 Apr;43(4):422-32. PubMed PMID: 2351614.
3: Gootz T, Retsema J, Girard A, Hamanaka E, Anderson M, Sokolowski S. In vitro activity of CP-65,207, a new penem antimicrobial agent, in comparison with those
of other agents. Antimicrob Agents Chemother. 1989 Aug;33(8):1160-6. PubMed PMID: 2679370; PubMed Central PMCID: PMC172617.
