WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H526519
CAS#: 91147-46-5
Description: UK 14819 is a selective thromboxane inhibitor.
Hodoodo Cat#: H526519
Name: UK 14819
CAS#: 91147-46-5
Chemical Formula: C11H12ClN5
Exact Mass: 249.08
Molecular Weight: 249.702
Elemental Analysis: C, 52.91; H, 4.84; Cl, 14.20; N, 28.05
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Synonym: UK 14819, UK-14819, UK14819
IUPAC/Chemical Name: (E)-5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-1,5-dihydroquinoxalin-6(4H)-imine
InChi Key: WSXYNFQZIXTPSW-REZTVBANSA-N
InChi Code: InChI=1S/C11H12ClN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4,9,13-14H,5-6H2,(H,15,16)/b17-7+
SMILES Code: ClC1C2=C(NC=CN2)C=C/C1=N\C3=NCCN3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 249.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Thaina P, Nott MW, Rand MJ. Effects of some imidazolidine alpha2-adrenoceptor agonists in rat isolated atria. J Auton Pharmacol. 1999 Jun;19(3):185-91. PubMed PMID: 10511476.
2: Thaina P, Nott MW, Rand MJ. Inhibition by alpha 2-adrenoceptor agonists of contractions of rabbit isolated colon elicited by pelvic nerve stimulation. J Auton Pharmacol. 1993 Apr;13(2):115-26. PubMed PMID: 8098041.