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Newest Products
Galeterone
CAT#: H205646
CAS#: 851983-85-2
Galeterone, also known as TOK-001 and NX41765; is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with pot…
GNE-0877
CAT#: H510258
CAS#: 1374828-69-9
GNE-0877, also known as DNL-201, is a highly potent and selective LRRK2 inhibitor. Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interes…
Efinaconazole
CAT#: H314247
CAS#: 164650-44-6
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fun…
AC710
CAT#: H406202
CAS#: 1351522-04-7 (free base)
AC710 is a potent, orally active, and selective platelet-derived growth factor receptor-family kinase inhibitor with potential anticancer activity. I…
JZL184
CAT#: H510320
CAS#: 1101854-58-3
JZL184 is highly selective, and potent MAGL inhibitor ( monoacylglycerol lipase inhibitor). JZL184 improves behavior and neural properties in Ts65Dn m…
Degarelix acetate
CAT#: H100255
CAS#: 934246-14-7 (acetate)
Degarelix, also known as FE-200486 and ASP-3550, is a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properti…
GSK429286A
CAT#: H510313
CAS#: 864082-47-3
GSK429286A is a selective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin-induce…
BRD4770
CAT#: H406572
CAS#: 1374601-40-7
BRD4770 is a novel histone methyltransferase inhibitor. BRD4770 reduced cellular levels of di- and trimethylated H3K9 without inducing apoptosis, indu…
GANT61
CAT#: H406570
CAS#: 500579-04-4
GANT61 is a small-molecule inhibitor of glioma-associated oncogene 1 (GLI1)- and GLI2-mediated transcription at the nuclear level that exerts its effe…
BX-471
CAT#: H510311
CAS#: 217645-70-0 (free base)
BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity f…
ML167
CAT#: H406566
CAS#: 1285702-20-6
ML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4. The Cdc2-like kinases (ClkÂ’s) and the …
PF-543 HCl
CAT#: H406142
CAS#: 1706522-79-3 (HCl)
PF-543 is a novel selective SK-1 inhibitor which inhibited SK-1 activity in a competitive manner with sphingosine. PF-543 inhibits SphK1 with a K(i) o…
MS7972
CAT#: H406551
CAS#: 352553-42-5
MS7972 is CREBBP inhibitor.
PF-573228
CAT#: H406126
CAS#: 869288-64-2
PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50= 4 nM). Displays 50 - 250-fold selectivity for FAK over other prote…
Taselisib (GDC0032)
CAT#: H205746
CAS#: 1282512-48-4
Taselisib, also known as GDC0032 or RG7606, is a selective, potent, orally bioavailable inhibitor of PI3Ka with a Ki = 0.2nM, and with reduced inhibit…
Taladegib
CAT#: H205529
CAS#: 1258861-20-9 (free base)
Taladegib, also known LY2940680, is a potent Hedgehog inhibitor with potential anticancer activity. LY2940680 inhibits cancer growth in cell lines con…
Nigericin sodium
CAT#: H406668
CAS#: 28643-80-3 (sodium)
Nigericin is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It also prevents viral activation and…
Brilanestrant
CAT#: H206041
CAS#: 1365888-06-7
Brilanestrant, also known as GDC-0810, ARN-810 and RG6046, an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robus…
SRPIN340
CAT#: H406657
CAS#: 218156-96-8
SRPIN340 is a selective serine arginine protein kinase (SRPK) 1 inhibitor with Ki = 0.89 μM. SRPK1 is a common binding partner of the E1^E4 protein of…
PF06447475
CAT#: H406655
CAS#: 1527473-33-1
PF06447475 is a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. Leucine rich repeat kinase 2 (LRRK2) has been ge…
FIIN-3
CAT#: H406653
CAS#: 1637735-84-2
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-3 is the first inhibitor that can potently inhibit t…
BAZ2-ICR
CAT#: H406642
CAS#: 1665195-94-7
BAZ2-ICR is an excellent chemical probe for functional studies of the BAZ2 bromodomains in vitro and in vivo. The bromodomain containing proteins BAZ2…
GSK2801
CAT#: H406639
CAS#: 1619994-68-1
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins…
SC66
CAT#: H406624
CAS#: 871361-88-5
SC66 is a novel and potent AKT inhibitor, which reduced cell viability in a dose- and time-dependent manner, inhibited colony formation and induced ap…
Wnt-C59
CAT#: H406605
CAS#: 1243243-89-1
Wnt-C59 is a potent porcupine (PORCN) inhibitor. Wnt-C59 inhibits PORCN activity in vitro at nanomolar concentrations, as assessed by inhibition of Wn…
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