WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H556179
CAS#: 436847-09-5 (free acid)
Description: MRS2365 is a highly potent and selective P2Y1 receptor agonist (EC50 = 0.4 nM). MRS2365 displays no activity at P2Y12 receptors and only very low agonist activity at P2Y13 receptors (at concentrations up to 1 μM). MRS2365 increases the upregulation of NTPDase1 by ATPγS.
Hodoodo Cat#: H556179
Name: MRS2365 free acid
CAS#: 436847-09-5 (free acid)
Chemical Formula: C13H19N5O9P2S
Exact Mass: 483.04
Molecular Weight: 483.329
Elemental Analysis: C, 32.31; H, 3.96; N, 14.49; O, 29.79; P, 12.82; S, 6.63
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 436847-09-5 (free acid) MRS2365 sodium,
Synonym: MRS2365 free acid; MRS-2365; MRS 2365; (N)-methanocarba-2MeSADP;
IUPAC/Chemical Name: ((1R,2R,3S,5S)-4-(6-amino-2-(methylthio)-9H-purin-9-yl)-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl)methyl trihydrogen diphosphate
InChi Key: WJDVSMBTIILRAJ-OCUKCYLTSA-N
InChi Code: InChI=1S/C13H19N5O9P2S/c1-30-12-16-10(14)6-11(17-12)18(4-15-6)7-5-2-13(5,9(20)8(7)19)3-26-29(24,25)27-28(21,22)23/h4-5,7-9,19-20H,2-3H2,1H3,(H,24,25)(H2,14,16,17)(H2,21,22,23)/t5-,7?,8+,9+,13+/m1/s1
SMILES Code: O=P(O)(O)OP(OC[C@]12[C@H]([C@H](C([C@]1(C2)[H])N3C=NC4=C(N=C(N=C34)SC)N)O)O)(O)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 483.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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