WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H123098
CAS#: 942518-29-8 (HCl)
Description: L-Azidohomoalanine HCl is an alkyl chain-based PROTAC linker.
Hodoodo Cat#: H123098
Name: L-Azidohomoalanine HCl
CAS#: 942518-29-8 (HCl)
Chemical Formula: C4H9ClN4O2
Exact Mass: 180.04
Molecular Weight: 180.590
Elemental Analysis: C, 26.60; H, 5.02; Cl, 19.63; N, 31.02; O, 17.72
Related CAS #: 120042-14-0 (free base) 942518-29-8 (HCl)
Synonym: 942518-29-8; (S)-2-Amino-4-azidobutanoic acid hydrochloride; L-Azidohomoalanine hydrochloride; (2S)-2-amino-4-azidobutanoic acid;hydrochloride;
IUPAC/Chemical Name: (S)-2-amino-4-azidobutanoic acid hydrochloride
InChi Key: MHHYJRIDKLZZEO-DFWYDOINSA-N
InChi Code: InChI=1S/C4H8N4O2.ClH/c5-3(4(9)10)1-2-7-8-6;/h3H,1-2,5H2,(H,9,10);1H/t3-;/m0./s1
SMILES Code: O=C(O)[C@@H](N)CCN=[N+]=[N-].[H]Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 180.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Roth S, Drewe WC, Thomas NR. A concise and scalable route to L-azidohomoalanine. Nat Protoc. 2010 Dec;5(12):1967-73. doi: 10.1038/nprot.2010.164. Epub 2010 Nov 18. PMID: 21127494.