WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H326862
CAS#: 134865-37-5 (tartrate)
Description: Meluadrine, also known as (R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81, is an β2 adrenergic receptor agonist potentially use to prevent preterm labor.
Hodoodo Cat#: H326862
Name: Meluadrine tartrate
CAS#: 134865-37-5 (tartrate)
Chemical Formula: C16H24ClNO8
Exact Mass: 0.00
Molecular Weight: 393.817
Elemental Analysis: C, 48.80; H, 6.14; Cl, 9.00; N, 3.56; O, 32.50
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Related CAS #: 134865-37-5 (tartrate) 134865-33-1 (free base)
Synonym: (R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81; Meluadrine tartrate
IUPAC/Chemical Name: (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-3-chlorophenol (2R,3R)-2,3-dihydroxysuccinate
InChi Key: VVIVBRYHTLRZGY-MBANBULQSA-N
InChi Code: InChI=1S/C12H18ClNO2.C4H6O6/c1-12(2,3)14-7-11(16)9-5-4-8(15)6-10(9)13;5-1(3(7)8)2(6)4(9)10/h4-6,11,14-16H,7H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
SMILES Code: O[C@@H](CNC(C)(C)C)C1=CC=C(O)C=C1Cl.O=C(O)[C@H](O)[C@@H](O)C(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info: Related CAS# CAS No. 134865-33-1(Meluadrine) CAS#134865-37-5(Meluadrine tartrate)
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The following data is based on the product molecular weight 393.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Matsuda Y, Kouno S, Sakamoto H, Ikenoue T. Effects of meluadrine tartrate on
maternal metabolic responses and fetal hemodynamics in pregnant goats. Jpn J
Pharmacol. 2002 Oct;90(2):114-20. PubMed PMID: 12419880.
2: Matsuda Y, Kouno S, Sakamoto H, Ikenoue T. Effects of meluadrine tartrate and
ritodrine hydrochloride on oxytocin-induced uterine contraction, uterine arterial
blood flow and maternal cardiovascular function in pregnant goats. Jpn J
Pharmacol. 2002 Oct;90(2):107-13. PubMed PMID: 12419879.
3: Matsuo K, Yamamoto Y, Kado N, Yamazaki M, Nagata O, Kato H, Tsuji A.
Racemization kinetics of meluadrine tartrate in aqueous solution. Chem Pharm Bull
(Tokyo). 2001 Jan;49(1):101-4. Erratum in: Chem Pharm Bull (Tokyo) 2001
Jun;49(6):794. PubMed PMID: 11201211.
