WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124491
CAS#: 2153458-32-1 (potassium)
Description: Azilsartan mepixetil is an angiotensin II receptor antagonist with renal and cardioprotective effects.
Hodoodo Cat#: H124491
Name: Azilsartan mepixetil potassium
CAS#: 2153458-32-1 (potassium)
Chemical Formula: C36H33KN6O8
Exact Mass: 716.20
Molecular Weight: 716.790
Elemental Analysis: C, 60.32; H, 4.64; K, 5.45; N, 11.72; O, 17.86
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Related CAS #: 1596357-16-2 (free base) 2153458-32-1 (potassium)
Synonym: NCH2TU7A5R; Azilsartan mepixetil potassium; UNII-NCH2TU7A5R; QR-01019K
IUPAC/Chemical Name: potassium 3-(4'-((2-ethoxy-7-((1-((((3,5,6-trimethylpyrazin-2-yl)methoxy)carbonyl)oxy)ethoxy)carbonyl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-5-oxo-1,2,4-oxadiazol-4-ide
InChi Key: YGZNXIVTPOLHFN-UHFFFAOYSA-M
InChi Code: InChI=1S/C36H34N6O8.K/c1-6-46-34-39-29-13-9-12-28(33(43)48-23(5)49-36(45)47-19-30-22(4)37-20(2)21(3)38-30)31(29)42(34)18-24-14-16-25(17-15-24)26-10-7-8-11-27(26)32-40-35(44)50-41-32;/h7-17,23H,6,18-19H2,1-5H3,(H,40,41,44);/q;+1/p-1
SMILES Code: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)[N-]5)C(=O)OC(C)OC(=O)OCC6=NC(=C(N=C6C)C)C.[K+]
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 716.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Hardin MD, Jacobs TF. Azilsartan. 2021 Jul 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 30860708.
2. Lam S. Azilsartan: a newly approved angiotensin II receptor blocker. Cardiol Rev. 2011 Nov-Dec;19(6):300-4. doi: 10.1097/CRD.0b013e31822e9ba3. PMID: 21983318.