WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124833
CAS#: 2173390-30-0 (fumarate)
Description: Zilurgisertib is a serine/threonine kinase inhibitor.
Hodoodo Cat#: H124833
Name: Zilurgisertib fumarate anhydrous
CAS#: 2173390-30-0 (fumarate)
Chemical Formula: C34H42N4O7
Exact Mass: 618.31
Molecular Weight: 618.730
Elemental Analysis: C, 66.00; H, 6.84; N, 9.06; O, 18.10
Related CAS #: 2173390-30-0 (fumarate) 2173389-57-4 (free base)
Synonym: EB17Z475NZ; Zilurgisertib fumarate; UNII-EB17Z475NZ; 2173390-30-0; NBU928 ANHYDROUS; NBU-928 ANHYDROUS; Zilurgisertib fumarate anhydrous; INCB000928 FUMARATE
IUPAC/Chemical Name: 2-amino-N-(4-hydroxybicyclo[2.2.2]octan-1-yl)-5-(4-((1R,5S)-3-(tetrahydro-2H-pyran-4-yl)-3-azabicyclo[3.1.0]hexan-1-yl)phenyl)nicotinamide fumarate
InChi Key: JYMHACJJTJNBGE-XESJLZEZSA-N
InChi Code: InChI=1S/C30H38N4O3.C4H4O4/c31-26-25(27(35)33-28-7-10-29(36,11-8-28)12-9-28)15-21(17-32-26)20-1-3-22(4-2-20)30-16-23(30)18-34(19-30)24-5-13-37-14-6-24;5-3(6)1-2-4(7)8/h1-4,15,17,23-24,36H,5-14,16,18-19H2,(H2,31,32)(H,33,35);1-2H,(H,5,6)(H,7,8)/b;2-1+/t23-,28?,29?,30+;/m1./s1
SMILES Code: C1COCCC1N2C[C@H]3C[C@]3(C2)C4=CC=C(C=C4)C5=CC(=C(N=C5)N)C(=O)NC67CCC(CC6)(CC7)O.C(=C/C(=O)O)\C(=O)O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 618.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
