WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H328209
CAS#: 30418-38-3 (free base)
Description: Tretoquinol, also known as AQ-110 and tretoquinol hydrochloride, is a β2-adrenergic receptor agonist used to treat asthma and chronic obstructive pulmonary disease. Although Tretoquinol possesses a catechol group, it was found not to be a substrate for catechol-O-methyl transferase and this is considered to account for its significantly prolonged action.
Hodoodo Cat#: H328209
Name: Tretoquinol
CAS#: 30418-38-3 (free base)
Chemical Formula: C19H23NO
Exact Mass: 345.16
Molecular Weight: 345.395
Elemental Analysis: C, 66.07; H, 6.71; N, 4.06; O, 23.16
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Related CAS #: 72534-66-8 (HCl hydrate) 18559-59-6 (HCl) 30418-38-3 (free base)
Synonym: Tretoquinol; tretoquinol hydrochloride; AQ-110; AQ110; AQ 110
IUPAC/Chemical Name: 1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
InChi Key: RGVPOXRFEPSFGH-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H23NO5/c1-23-17-7-11(8-18(24-2)19(17)25-3)6-14-13-10-16(22)15(21)9-12(13)4-5-20-14/h7-10,14,20-22H,4-6H2,1-3H3
SMILES Code: OC1=CC2=C(C(CC3=CC(OC)=C(OC)C(OC)=C3)NCC2)C=C1O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info: Related CAS# 30418-38-3 (free base) 18559-59-6 (HCl)
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The following data is based on the product molecular weight 345.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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