Auramine acetate

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H341131

CAS#: 5089-20-3 (acetate)

Description: Auramine is a dye

Chemical Structure

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Auramine acetate
CAS# 5089-20-3 (acetate)
Instruction

Theoretical Analysis

Hodoodo Cat#: H341131
Name: Auramine acetate
CAS#: 5089-20-3 (acetate)
Chemical Formula: C19H25N3O2
Exact Mass: 267.17
Molecular Weight: 327.430
Elemental Analysis: C, 69.70; H, 7.70; N, 12.83; O, 9.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 492-80-8 (free base)   2465-27-2 (HCl)   5089-20-3 (acetate)    

Synonym: Auramine acetate, C.I. Basic Yellow 2, acetate.

IUPAC/Chemical Name: 4,4'-Carbonimidoylbis(N,N-dimethylaniline) acetate

InChi Key: IUBRQGNYFJWZCB-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H21N3.C2H4O2/c1-19(2)15-9-5-13(6-10-15)17(18)14-7-11-16(12-8-14)20(3)4;1-2(3)4/h5-12,18H,1-4H3;1H3,(H,3,4)

SMILES Code: N=C(C1=CC=C(C=C1)N(C)C)C2=CC=C(C=C2)N(C)C.CC(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 327.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kamariza M, Shieh P, Ealand CS, Peters JS, Chu B, Rodriguez-Rivera FP, Babu Sait MR, Treuren WV, Martinson N, Kalscheuer R, Kana BD, Bertozzi CR. Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe. Sci Transl Med. 2018 Feb 28;10(430). pii: eaam6310. doi: 10.1126/scitranslmed.aam6310. PubMed PMID: 29491187.

2: Law YN, Jian H, Lo NWS, Ip M, Chan MMY, Kam KM, Wu X. Low cost automated whole smear microscopy screening system for detection of acid fast bacilli. PLoS One. 2018 Jan 22;13(1):e0190988. doi: 10.1371/journal.pone.0190988. eCollection 2018. PubMed PMID: 29357378; PubMed Central PMCID: PMC5777646.

3: Fideles RA, Ferreira GMD, Teodoro FS, Adarme OFH, da Silva LHM, Gil LF, Gurgel LVA. Trimellitated sugarcane bagasse: A versatile adsorbent for removal of cationic dyes from aqueous solution. Part I: Batch adsorption in a monocomponent system. J Colloid Interface Sci. 2018 Apr 1;515:172-188. doi: 10.1016/j.jcis.2018.01.025. Epub 2018 Jan 6. PubMed PMID: 29335184.

4: Noori MY, Ali F, Ali Z, Sharafat S. Comparison Of Ziehl-Neelsen Based Light Microscopy With Led Fluorescent Microscopy For Tuberculosis Diagnosis: An Insight From A Limited Resource-High Burden setting. J Ayub Med Coll Abbottabad. 2017 Oct-Dec;29(4):577-579. PubMed PMID: 29330981.

5: Maguga-Phasha NTC, Munyai NS, Mashinya F, Makgatho ME, Mbajiorgu EF. Genetic diversity and distribution of Mycobacterium tuberculosis genotypes in Limpopo, South Africa. BMC Infect Dis. 2017 Dec 12;17(1):764. doi: 10.1186/s12879-017-2881-z. PubMed PMID: 29233106; PubMed Central PMCID: PMC5727936.

6: Workineh M, Maru M, Seman I, Bezu Z, Negash M, Melku M, Gize A, Shibabaw A. Agreement between Direct Fluorescent Microscopy and Ziehl-Neelsen Concentration Techniques in Detection of Pulmonary Tuberculosis in Northwest Ethiopia. Ethiop J Health Sci. 2017 Sep;27(5):459-464. PubMed PMID: 29217950; PubMed Central PMCID: PMC5615006.

7: Chaudhary S, Sharma J, Kaith BS, Yadav S, Sharma AK, Goel A. Gum xanthan-psyllium-cl-poly(acrylic acid-co-itaconic acid) based adsorbent for effective removal of cationic and anionic dyes: Adsorption isotherms, kinetics and thermodynamic studies. Ecotoxicol Environ Saf. 2018 Mar;149:150-158. doi: 10.1016/j.ecoenv.2017.11.030. Epub 2017 Nov 20. PubMed PMID: 29156307.

8: Teodoro FS, Elias MMC, Ferreira GMD, Adarme OFH, Savedra RML, Siqueira MF, da Silva LHM, Gil LF, Gurgel LVA. Synthesis and application of a new carboxylated cellulose derivative. Part III: Removal of auramine-O and safranin-T from mono- and bi-component spiked aqueous solutions. J Colloid Interface Sci. 2018 Feb 15;512:575-590. doi: 10.1016/j.jcis.2017.10.083. Epub 2017 Oct 25. PubMed PMID: 29100162.

9: He F, He Y, Zheng X, Wang R, Lu J, Dai Z, Ma S. Screening of Chemical Dyes in Traditional Chinese Medicine by HPTLC-MS. J AOAC Int. 2017 Oct 17. doi: 10.5740/jaoacint.17-0298. [Epub ahead of print] PubMed PMID: 29037280.

10: Chen DY, Zhang H, Feng JL, Zeng D, Ding L, Liu XJ, Li BR. Research on the Determination of 10 Industrial Dyes in Foodstuffs. J Chromatogr Sci. 2017 Nov 1;55(10):1021-1025. doi: 10.1093/chromsci/bmx070. PubMed PMID: 28977358.

11: Kammüller M, Tsai TF, Griffiths CE, Kapoor N, Kolattukudy PE, Brees D, Chibout SD, Safi J Jr, Fox T. Inhibition of IL-17A by secukinumab shows no evidence of increased Mycobacterium tuberculosis infections. Clin Transl Immunology. 2017 Aug 25;6(8):e152. doi: 10.1038/cti.2017.34. eCollection 2017 Aug. PubMed PMID: 28868144; PubMed Central PMCID: PMC5579471.

12: Dhadke S, Dhadke V, Giram A. Auramine-o (Synthetic Yellow Cow Dung Powder) Poisoning: Rare but Fatal. J Assoc Physicians India. 2017 Jul;65(7):18-20. PubMed PMID: 28792163.

13: Jafari M, Rahimi MR, Ghaedi M, Javadian H, Asfaram A. Fixed-bed column performances of azure-II and auramine-O adsorption by Pinus eldarica stalks activated carbon and its composite with zno nanoparticles: Optimization by response surface methodology based on central composite design. J Colloid Interface Sci. 2017 Dec 1;507:172-189. doi: 10.1016/j.jcis.2017.07.056. Epub 2017 Jul 24. PubMed PMID: 28787618.

14: Qi F, Jian N, Qian L, Cao W, Xu Q, Li J. Development and optimization of a novel sample preparation method cored on functionalized nanofibers mat-solid-phase extraction for the simultaneous efficient extraction of illegal anionic and cationic dyes in foods. Anal Bioanal Chem. 2017 Sep;409(24):5697-5709. doi: 10.1007/s00216-017-0510-8. Epub 2017 Jul 24. PubMed PMID: 28741107.

15: Tung JC, Huang WC, Yang JC, Chen GY, Fan CC, Chien YC, Lin PS, Candice Lung SC, Chang WC. Auramine O, an incense smoke ingredient, promotes lung cancer malignancy. Environ Toxicol. 2017 Nov;32(11):2379-2391. doi: 10.1002/tox.22451. Epub 2017 Jul 19. PubMed PMID: 28722353; PubMed Central PMCID: PMC5655719.

16: Awasthi AA, Singh PK. Stimulus-Responsive Supramolecular Aggregate Assembly of Auramine O Templated by Sulfated Cyclodextrin. J Phys Chem B. 2017 Jun 29;121(25):6208-6219. doi: 10.1021/acs.jpcb.7b03592. Epub 2017 Jun 19. PubMed PMID: 28574272.

17: Zhang H, Li Z, Chen T, Qin B. Quantitative determination of Auramine O by terahertz spectroscopy with 2DCOS-PLSR model. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Sep 5;184:335-341. doi: 10.1016/j.saa.2017.05.017. Epub 2017 May 10. PubMed PMID: 28528254.

18: Bazrafshan AA, Ghaedi M, Hajati S, Naghiha R, Asfaram A. Synthesis of ZnO-nanorod-based materials for antibacterial, antifungal activities, DNA cleavage and efficient ultrasound-assisted dyes adsorption. Ecotoxicol Environ Saf. 2017 Aug;142:330-337. doi: 10.1016/j.ecoenv.2017.04.011. Epub 2017 Apr 28. PubMed PMID: 28437724.

19: Elston DM, Liranzo MO, Scollard DM. Comparing the sensitivity of auramine-rhodamine fluorescence to polymerase chain reaction in the detection of Mycobacterium leprae in Fite-negative tissue sections. J Am Acad Dermatol. 2017 May;76(5):992-993. doi: 10.1016/j.jaad.2016.11.045. PubMed PMID: 28411775.

20: Akduman Alaşehir E, Balıkçı A, Partal M, Çatmabacak G, Yaman G. [Evaluation of mycobacterial microscopy and culture results of Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital: A 3-year analysis]. Tuberk Toraks. 2016 Sep;64(3):211-216. Turkish. PubMed PMID: 28366154.