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Auramine free base
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WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H592073

CAS#: 492-80-8 (free base)

Description: Auramine is a dye. Auramine O (AO) is a banned food additive and has been classified as an illegal colourant.

Chemical Structure

Auramine free base

CAS# 492-80-8 (free base)

Instruction

Theoretical Analysis

Hodoodo Cat#: H592073
Name: Auramine free base
CAS#: 492-80-8 (free base)
Chemical Formula: C17H21N3
Exact Mass: 267.17
Molecular Weight: 267.380
Elemental Analysis: C, 76.37; H, 7.92; N, 15.72

Price and Availability

Size	Price	Availability	Quantity
25mg	USD 385	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. Hodoodo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Auramine; C.I. Solvent Yellow 34;

IUPAC/Chemical Name: 4,4'-Carbonimidoylbis(N,N-dimethylaniline)

InChi Key: JPIYZTWMUGTEHX-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H21N3/c1-19(2)15-9-5-13(6-10-15)17(18)14-7-11-16(12-8-14)20(3)4/h5-12,18H,1-4H3

SMILES Code: N=C(C1=CC=C(C=C1)N(C)C)C2=CC=C(C=C2)N(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 267.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Wang X, Duan HL, Ma SY, Wang J, Zhan HY, Zhang ZQ. Selective adsorption and separation of illegal cationic dyes from foodstuffs with anionic polyelectrolyte functionalization of metal-organic frameworks. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Jul 5. doi: 10.1080/19440049.2018.1492154. [Epub ahead of print] PubMed PMID: 29975171.

2: da Silva MB, Portela JM, Li W, Jackson M, Gonzalez-Juarrero M, Hidalgo AS, Belisle JT, Bouth RC, Gobbo AR, Barreto JG, Minervino AHH, Cole ST, Avanzi C, Busso P, Frade MAC, Geluk A, Salgado CG, Spencer JS. Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos. PLoS Negl Trop Dis. 2018 Jun 28;12(6):e0006532. doi: 10.1371/journal.pntd.0006532. eCollection 2018 Jun. PubMed PMID: 29953440.

3: Ahmad F, Rehman A, Jadoon O. Histological Comparison Of Two Staining Methods In Identification Of Mycobacterium Tuberculosis In Granulomatous Lymphadenitis. J Ayub Med Coll Abbottabad. 2018 Apr-Jun;30(2):159-162. PubMed PMID: 29938410.

4: Park D, Kim JC. Monoolein cubic phases containing cinnamic acid, poly(ethyleneimine) and gold nanoparticle and their UV- and NIR-responsive release property. Int J Pharm. 2018 Jun 19. pii: S0378-5173(18)30442-3. doi: 10.1016/j.ijpharm.2018.06.044. [Epub ahead of print] PubMed PMID: 29933061.

5: Zinserling VA, Agapov MM, Orlov AN. [The informative value of various methods for identifying acid-fast bacilli in relation to the degree of tuberculosis process activity]. Arkh Patol. 2018;80(3):40-45. doi: 10.17116/patol201880340-45. Russian. PubMed PMID: 29927439.

6: Mugala L, Siwila J, Saasa N, Pandey GS. Prevalence of Cryptosporidium spp. oocysts in dogs in Lusaka district of Zambia. Vet World. 2018 May;11(5):585-589. doi: 10.14202/vetworld.2018.585-589. Epub 2018 May 6. PubMed PMID: 29915495; PubMed Central PMCID: PMC5993767.

7: Zheng H, He J, Wang L, Zhang R, Ding Z, Hu W. Risk Factors and Spatial Clusters of Cryptosporidium Infection among School-Age Children in a Rural Region of Eastern China. Int J Environ Res Public Health. 2018 May 6;15(5). pii: E924. doi: 10.3390/ijerph15050924. PubMed PMID: 29734766; PubMed Central PMCID: PMC5981963.

8: Selepe MM, van Wyk AC, Hoek KGP, Prince Y, van Helden PD, Warren RM, Wright CA. Papanicolaou induced fluorescence, Ziehl-Neelsen and Auramine O stains on lymph node fine needle aspiration biopsy specimens from children: A comparative study. Diagn Cytopathol. 2018 Jul;46(7):589-592. doi: 10.1002/dc.23956. Epub 2018 May 3. PubMed PMID: 29722172.

9: Zhang Q, Zhang Q, Sun BQ, Liu C, Su AN, Wang XH, Liu N, Zhang J, Kang J, Hou G. GeneXpert MTB/RIF for rapid diagnosis and rifampin resistance detection of endobronchial tuberculosis. Respirology. 2018 Apr 24. doi: 10.1111/resp.13316. [Epub ahead of print] PubMed PMID: 29691960.

10: Moreira ADS, Baptista CT, Brasil CL, Valente JSS, Bruhn FRP, Pereira DIB. Risk factors and infection due to Cryptosporidium spp. in dogs and cats in southern Rio Grande do Sul. Rev Bras Parasitol Vet. 2018 Jan-Mar;27(1):113-118. doi: 10.1590/S1984-296120180012. Epub 2018 Mar 12. PubMed PMID: 29538486.

11: Kamariza M, Shieh P, Ealand CS, Peters JS, Chu B, Rodriguez-Rivera FP, Babu Sait MR, Treuren WV, Martinson N, Kalscheuer R, Kana BD, Bertozzi CR. Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe. Sci Transl Med. 2018 Feb 28;10(430). pii: eaam6310. doi: 10.1126/scitranslmed.aam6310. PubMed PMID: 29491187; PubMed Central PMCID: PMC5985656.

12: Law YN, Jian H, Lo NWS, Ip M, Chan MMY, Kam KM, Wu X. Low cost automated whole smear microscopy screening system for detection of acid fast bacilli. PLoS One. 2018 Jan 22;13(1):e0190988. doi: 10.1371/journal.pone.0190988. eCollection 2018. PubMed PMID: 29357378; PubMed Central PMCID: PMC5777646.

13: Fideles RA, Ferreira GMD, Teodoro FS, Adarme OFH, da Silva LHM, Gil LF, Gurgel LVA. Trimellitated sugarcane bagasse: A versatile adsorbent for removal of cationic dyes from aqueous solution. Part I: Batch adsorption in a monocomponent system. J Colloid Interface Sci. 2018 Apr 1;515:172-188. doi: 10.1016/j.jcis.2018.01.025. Epub 2018 Jan 6. PubMed PMID: 29335184.

14: Noori MY, Ali F, Ali Z, Sharafat S. Comparison Of Ziehl-Neelsen Based Light Microscopy With Led Fluorescent Microscopy For Tuberculosis Diagnosis: An Insight From A Limited Resource-High Burden setting. J Ayub Med Coll Abbottabad. 2017 Oct-Dec;29(4):577-579. PubMed PMID: 29330981.

15: Maguga-Phasha NTC, Munyai NS, Mashinya F, Makgatho ME, Mbajiorgu EF. Genetic diversity and distribution of Mycobacterium tuberculosis genotypes in Limpopo, South Africa. BMC Infect Dis. 2017 Dec 12;17(1):764. doi: 10.1186/s12879-017-2881-z. PubMed PMID: 29233106; PubMed Central PMCID: PMC5727936.

16: Workineh M, Maru M, Seman I, Bezu Z, Negash M, Melku M, Gize A, Shibabaw A. Agreement between Direct Fluorescent Microscopy and Ziehl-Neelsen Concentration Techniques in Detection of Pulmonary Tuberculosis in Northwest Ethiopia. Ethiop J Health Sci. 2017 Sep;27(5):459-464. PubMed PMID: 29217950; PubMed Central PMCID: PMC5615006.

17: Chaudhary S, Sharma J, Kaith BS, Yadav S, Sharma AK, Goel A. Gum xanthan-psyllium-cl-poly(acrylic acid-co-itaconic acid) based adsorbent for effective removal of cationic and anionic dyes: Adsorption isotherms, kinetics and thermodynamic studies. Ecotoxicol Environ Saf. 2018 Mar;149:150-158. doi: 10.1016/j.ecoenv.2017.11.030. Epub 2017 Nov 20. PubMed PMID: 29156307.

18: Teodoro FS, Elias MMC, Ferreira GMD, Adarme OFH, Savedra RML, Siqueira MF, da Silva LHM, Gil LF, Gurgel LVA. Synthesis and application of a new carboxylated cellulose derivative. Part III: Removal of auramine-O and safranin-T from mono- and bi-component spiked aqueous solutions. J Colloid Interface Sci. 2018 Feb 15;512:575-590. doi: 10.1016/j.jcis.2017.10.083. Epub 2017 Oct 25. PubMed PMID: 29100162.

19: He F, He Y, Zheng X, Wang R, Lu J, Dai Z, Ma S. Screening of Chemical Dyes in Traditional Chinese Medicine by HPTLC-MS. J AOAC Int. 2018 May 1;101(3):686-694. doi: 10.5740/jaoacint.17-0298. Epub 2017 Oct 17. PubMed PMID: 29037280.

20: Chen DY, Zhang H, Feng JL, Zeng D, Ding L, Liu XJ, Li BR. Research on the Determination of 10 Industrial Dyes in Foodstuffs. J Chromatogr Sci. 2017 Nov 1;55(10):1021-1025. doi: 10.1093/chromsci/bmx070. PubMed PMID: 28977358.

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